Results 41 to 50 of about 24,133,917 (300)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Analisi del valore aggiunto pro capite: una tassonomia dei Sistemi Locali del Lavoro italiani attraverso la shift-share analysis con struttura spaziale

open access: yesCybergeo, 2011
Economic studies on micro-territorial settings have received growing attention in the social sciences, highlighting the complexity of social and economic mechanisms in macro-economic dynamics. The aim of this paper is to analyze the spatial influences on
Massimo Pasquariello
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Determining Leading Economic Sectors, by Large Distribution or Extreme Growth?

open access: yesThe Journal of Indonesia Sustainable Development Planning, 2020
Leading economic sector on Tulungagung Regency determined by sector contribution on GRDP. These sectors expected can be a booster to economic growth. But Economic Growth in Tulungagung Regency was still slower than East Java Province.
Alfian Rosadi
doaj   +1 more source

Employment Changes in the European Economic Community: A Shift-Share Analysis [PDF]

open access: yesReview of Regional Studies, 1995
The countries that make up the EC ” … are well into the process of complete economic integration” (Hailstones and Mastrianna 1991). The EC has become an established free trade zone and as such has become a relatively homogeneous economic region. While many studies have investigated the overall impact of the EC, few have focused on intraregional ...
Margaret A. Ray, John T. Harvey
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Study of the Utilisation of Commercial Accommodations with Special Regard to Northern Hungary and Northern Great Plain

open access: yesTheory, Methodology, Practice, 2011
Increasing the accommodation supply is a top priority of tourism development at present. Tourism in Hungary has shown significant results since the 90s.
Zsolt Péter
doaj  

Differences in the land rent among EU countries

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013
The aim of the paper is to assess the differences in the influence of land rent on farm production efficiencies by region, farming type and LFA. In terms of the cost of rents there are significant differences among countries within the European Union ...
Jana Lososová   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Description and spatial analysis of employment change in New Zealand regions 1986-2001 [PDF]

open access: yes, 2005
Over the last two decades New Zealand has undergone fundamental economic restructuring, and phases of slow and rapid growth, which have resulted in some dramatic changes in the regional economies.
Baxendine, Sandra   +2 more
core  

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