Results 111 to 120 of about 24,131,008 (297)

Regional specialization and employment dynamics in transition countries [PDF]

open access: yes
Trade reorientation and transition to a market economy in Central and East European countries have resulted in structural change, i.e. industrial restructuring and labor reallocation across sectors and regions.
Traistaru, Iulia, Wolff, Guntram B.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Klasifikasi Pertumbuhan, Sektor Basis dan Kompetitif Kota Jambi [PDF]

open access: yesJurnal Perspektif Pembiayaan dan Pembangunan Daerah, 2015
This study aims to determine the classification of economic growth in the city of Jambi, base and non-base sectors in the economy of the city of Jambi, Competitive sectors in the economy of the city of Jambi and to determine the leading sectors in Jambi ...
Yusral, Junaidi, Adi Bhakti
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Regional Productivity Differentials in Poland, Hungary and the Czech Republic [PDF]

open access: yes
This paper starts by describing the distribution of GVA, employment and productivity growth across the regions of Poland, Hungary and the Czech Republic.
Julie Le Gallo   +3 more
core  

POST-CRISIS ECONOMIC SPECIALISATION PATTERNS OF ARGES COUNTY IN ROMANIA AND THE EU. MOVING TOWARDS SMART SPECIALIZATION [PDF]

open access: yesStrategii Manageriale, 2013
Under the new European regional policy framework for 2014 – 2020, smart specialization is a key issue meant to highglight the unique characteristics and assets of each country/ region and to rally regional stakeholders and resources around an excellence ...
Ovidiu, PUIU, Cristina, SERBANICA
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Income Disparities and Trends in Manufactured Exports Across the States and Territories of Australia: 1989/90 - 2000/01 [PDF]

open access: yes
This paper documents differences in the levels and growth rates of manufactured exports across the Australian states and territories over the period 1989/90 - 2000/01 and then re-interprets these differences using shift-share analysis.
Jayanthakumaran, Kankesu, Neri, Frank
core  

Shift-Share Analysis, Appalachian Counties [PDF]

open access: yes, 2020
In County-level CIE Supply Chain Analysis, the second of five p a rts o f A n E c onomic A n alysis of the Appalachian Coal Industry Ecosystem posted to the Commission’s website in January of 2018, we developed a set of metrics that were used to provide ...
Járosi, Péter, Jackson, Randall
core  

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