Results 91 to 100 of about 24,240,175 (300)
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Regional Economic growth and accessibility: The case of the Netherlands [PDF]
Shift-share is a popular, relatively easy to apply, tool in spatial analysis. Upon its initial development and use in the 1970s the literature has shown that serious drawbacks of the shift-share technique should be noted (e.g., lack of theoretical basis,
Cornelis Martijn Van der Heide +3 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A Shift-Share Analysis of Regional and Sectoral Productivity Growth in Contemporary Mexico [PDF]
This paper presents a shift-share analysis of labor productivity in Mexico. Following a brief review of the role of rising labor productivity in recent economic growth, the analysis focuses on 1) the possible contribution to increases in labor ...
Reynolds, C.W.
core +1 more source
An Approach to an Intersection Traffic Delay Study Based on Shift-Share Analysis
Intersection traffic delay research has traditionally placed greater emphasis on the study of through and left-turning vehicles than right-turning ones, which often renders existing methods or models inapplicable to intersections with heavy pedestrian ...
Jianfeng Xi +3 more
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Competition among the Manufacturing Exporters of China and ASEAN in the U.S. Market, 1994-2001 [PDF]
This paper aims to compare changes in the competitive position of China and ASEAN-4 (Indonesia, Malaysia, Singapore and Thailand) as exporters of manufactured goods to the US market between 1994 and 2001.
Muhammad Zikri
core
Resulting from the 21st UN Climate Change Conference (COP21) in Paris in 2015, the European Union’s (EU) current climate and energy objective is to reduce greenhouse gas (GHG) emissions by 40% below 1990 levels by 2030, and transportation must play a ...
Olaf Jonkeren, Jan Francke, Johan Visser
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
MEASURING ECONOMIC GROWTH IN RURAL COMMUNITIES: THE SHIFT-SHARE APPROACH [PDF]
Community/Rural/Urban Development,
Gordon, John, Darling, David L.
core

