Results 121 to 130 of about 1,903,301 (306)

Competition among the Manufacturing Exporters of China and ASEAN in the U.S. Market, 1994-2001 [PDF]

open access: yes
This paper aims to compare changes in the competitive position of China and ASEAN-4 (Indonesia, Malaysia, Singapore and Thailand) as exporters of manufactured goods to the US market between 1994 and 2001.
Muhammad Zikri
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Regional Productivity Differentials in Poland, Hungary and the Czech Republic [PDF]

open access: yes
This paper starts by describing the distribution of GVA, employment and productivity growth across the regions of Poland, Hungary and the Czech Republic.
Julie Le Gallo   +3 more
core  

The Theory and Practice of Corporate Citizenship in Nigeria: A Petroleum Industry Beneficiary Analysis [PDF]

open access: yes, 2006
With the aid of ethnographic data obtained in Nigeria's oil and gas region (the Niger Delta), and relevant secondary data, this article makes a case for a beneficiary-centred approach to corporate citizenship analysis, and thus urges a shift from the ...
Wilson Akpan
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Determination of the Regional Economy Leading Sectors in Indonesia

open access: yesJurnal Ekonomi Pembangunan: Kajian Masalah Ekonomi dan Pembangunan, 2015
Economic growth and its process are the main condition for the sustainability of the regional economic development. Because of the continuing population growth means economic needs also increase so that additional revenue required each year.
Fitri Amalia
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

The Impact of Transition and Economic Integration on Manufacturing Employment Change: An Assessment for the Regions of the European Union New Member-States. [PDF]

open access: yes
The spatial and structural dynamics generated (or released) in the contexts of the parallel and interacting processes of transition and economic integration have already left a clear mark in the economic landscape of the EU new member-states.
Dimitrios Kallioras
core  

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