Results 71 to 80 of about 285,452 (262)

Reflexos territoriais do processo de reestruturação industrial em Portugal Continental na década de oitenta [PDF]

open access: yesFinisterra - Revista Portuguesa de Geografia, 1996
INDUSTRIAL RESTRUCTURING IN PORTUGAL IN THE EIGHTIES - This paper analyses the territorial changes un manufacturing activity in mainland Portugal during the eighties. A shift-share analysis was applied to regional employment.
Nuno Costa, Eduarda Costa
doaj  

An Approach to an Intersection Traffic Delay Study Based on Shift-Share Analysis

open access: yesInformation, 2015
Intersection traffic delay research has traditionally placed greater emphasis on the study of through and left-turning vehicles than right-turning ones, which often renders existing methods or models inapplicable to intersections with heavy pedestrian ...
Jianfeng Xi   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

A shift-share based tool for assessing the contribution of a modal shift to the decarbonisation of inland freight transport

open access: yesEuropean Transport Research Review, 2019
Resulting from the 21st UN Climate Change Conference (COP21) in Paris in 2015, the European Union’s (EU) current climate and energy objective is to reduce greenhouse gas (GHG) emissions by 40% below 1990 levels by 2030, and transportation must play a ...
Olaf Jonkeren, Jan Francke, Johan Visser
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Perspective clusters in Slovakia: the case of Banská Bystrica region

open access: yesForum Scientiae Oeconomia, 2016
The paper focuses on the identification of perspective clusters in BanskáBystrica region. It uses national and regional data about the employment and anal-yses the regional and industrial share of businesses on the total employment (both in Slovakia and
Ľuboš Elexa   +3 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Regional convergence in Europe and the industry mix: a shift-share analysis [PDF]

open access: yesRegional Science and Urban Economics, 2000
Financial support from the research grant CICYT PB96-0897 and the Fundació d’Economía Analítica is gratefully acknowledged.
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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