Results 51 to 60 of about 24,131,008 (297)

ANALISIS PEMBANGUNAN WILAYAH BERBASIS KOMODITI UNGGULAN KABUPATEN PASAMAN, SUMATERA BARAT [PDF]

open access: yesEconomica, 2015
Province and municipality as region of national region expected can execute acceleration of development of area economics focused at its products in order not to drop behind in emulation of free trade.
Yolamalinda
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Analisi del valore aggiunto pro capite: una tassonomia dei Sistemi Locali del Lavoro italiani attraverso la shift-share analysis con struttura spaziale

open access: yesCybergeo, 2011
Economic studies on micro-territorial settings have received growing attention in the social sciences, highlighting the complexity of social and economic mechanisms in macro-economic dynamics. The aim of this paper is to analyze the spatial influences on
Massimo Pasquariello
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Study of the Utilisation of Commercial Accommodations with Special Regard to Northern Hungary and Northern Great Plain

open access: yesTheory, Methodology, Practice, 2011
Increasing the accommodation supply is a top priority of tourism development at present. Tourism in Hungary has shown significant results since the 90s.
Zsolt Péter
doaj  

Menemukan Strategi Pengembangan Kawasan Industri Melalui Analisis Sektor Unggulan Kota Binjai

open access: yesJurnal Wilayah dan Lingkungan, 2016
Manufacturing industry is a leading sector that has potentials for promoting rapid growth in a region. The growth that relies on the industrial sector is driven by the sales of production, employment, and other multiplier effects so that many districts ...
Dessy Eresina Pinem
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Employment Changes in the European Economic Community: A Shift-Share Analysis [PDF]

open access: yesReview of Regional Studies, 1995
The countries that make up the EC ” … are well into the process of complete economic integration” (Hailstones and Mastrianna 1991). The EC has become an established free trade zone and as such has become a relatively homogeneous economic region. While many studies have investigated the overall impact of the EC, few have focused on intraregional ...
Margaret A. Ray, John T. Harvey
openaire   +2 more sources

The structural and geographical analysis of occupational diseases in Poland in the years 2003–2010

open access: yesStudia Regionalne i Lokalne, 2013
The paper uses the advanced spatial shift-share method to examine the tendency of some occupational diseases to occur in particular regions and sectors of the economy.
Anna Weszczak, Aneta Staszek
doaj   +1 more source

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