Results 21 to 30 of about 293,216 (302)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The Competitive Effect in Shift Share Analysis: A Will of the Wisp? [PDF]

open access: yesReview of Regional Studies, 1981
This study takes a new approach to the examination of the competitive component. It is based on the proposition that a region’s competitive advantage in an industry is one determinant of industry investment in the region. If a region’s competitive advantage increases, private decision-makers can be expected to increase investment in the region.
Tim G. Ireland, Ronald L. Moomaw
openaire   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Regional Growth and Development in Hungary and Romania [PDF]

open access: yesRomanian Review of Regional Studies, 2009
The paper presents how economic structural changes affect a region’s economic growth and development. To show this effect is not that easy since changes of economic structure take time, and the result of changes appear shifted in time in the examined ...
ILDIKÓ KNEISZ
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Economic Development of Jayapura Regency, Papua Province Based on the Potential of Leading Regional Economic Sectors

open access: yesJurnal Penelitian Ekonomi dan Bisnis
This study aims to identify and analyze the economic sectors that are the leading sectors and potential sectors of the region that can be developed to improve the regional economy of Jayapura Regency, using time series data from 2013-2021 which were ...
Stephany Inagama Timisela   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Theoretical basis for a method of distribution of market share changes in international trade Base teórica para um método de distribuição de mudanças de participações de mercado no comércio internacional

open access: yesRevista de Economia Contemporânea, 2010
Chami's method for calculating how much of an exporter's market share change can be attributed to each competitor has regularly been applied in the literature, but it has not been related to any theory yet.
J. Chami Batista
doaj   +1 more source

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