Results 61 to 70 of about 285,487 (262)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

A Dynamic Shift-Share Analysis of Economic Growth in West Virginia

open access: yesJournal of Rural and Community Development, 2012
A regional economy consists of industries with a variety of economic potentials. A growth or decline in any of these sectors affects the overall growth of the economy.
Saman Janaranjana Herath Bandara   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

АНАЛИЗ КОНКУРЕНТОСПОСОБНОСТИ И СТРУКТУРНЫХ СДВИГОВ В ЭКОНОМИКЕ РЕГИОНОВ СИБИРСКОГО ФЕДЕРАЛЬНОГО ОКРУГА

open access: yesЭкономика, профессия, бизнес
В статье анализируется структура экономики и отраслевого роста регионов Сибирского федерального округа в 2022-2023 гг. с помощью метода анализа конкурентоспособности и структурных сдвигов (метод Shift Share Analys).
Данила Александрович Доценко
doaj   +1 more source

Growth of citrus production among the Euro-Mediterranean countries: political implications and empirical findings

open access: yesSpanish Journal of Agricultural Research, 2013
The agricultural matter has always played an important role in holding back the Euro-Mediterranean integration process due to the strong complementarity of the agricultures of the coastal countries which share excellent products including citrus fruits ...
E. Schimmenti, V. Borsellino, A. Galati
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Regional convergence in Europe and the industry mix: a shift-share analysis [PDF]

open access: yesRegional Science and Urban Economics, 2000
Financial support from the research grant CICYT PB96-0897 and the Fundació d’Economía Analítica is gratefully acknowledged.
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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