Results 61 to 70 of about 293,216 (302)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Regional and structural factors in Swedish regional growth during the 1990s

open access: yesCybergeo, 2006
Based on the Swedish Standard Industrial Classification and individual longitudinal data, by using the shift-share analysis method, Swedish regional employment growth during the 1990s has been decomposed into two components—growth due to an endogenous ...
Li Wenjuan
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Shift–share Analysis of manufacturing as a measuring instrument for Human Resource Management

open access: yesSA Journal of Human Resource Management, 2009
Shift-share analysis of employment as a measuring instrument for human resource management is proposed by this study. The results obtained through this technique can assist human resource management on the macro-level in making informed and strategic ...
Ewert Philippus Kleynhans
doaj   +1 more source

Path Based Shift-Share Analysis -Using Additional Information in Decomposing Regional Economic Changes [PDF]

open access: yes
Shift-Share analysis is a well-known methodology frequently used to obtain insights into the determinants of regional growth processes. It can address many issues, such as output growth, employment growth and productivity growth.
Esteban Fernández   +2 more
core  

East Coast Economic Region From The Perspective Of Shift-Share Analysis [PDF]

open access: yes, 2011
The Malaysian government is promoting a new regional development method particularly by promoting a regional development corridor. Our paper tries to examine this new development from the perspective of regional shift-share analysis that covers the ...
Zakariah, Abdul Rashid   +2 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

A Dynamic Shift-Share Analysis of Economic Growth in West Virginia

open access: yesJournal of Rural and Community Development, 2012
A regional economy consists of industries with a variety of economic potentials. A growth or decline in any of these sectors affects the overall growth of the economy.
Saman Janaranjana Herath Bandara   +2 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Non-Cointegration and Econometric Evaluation of Models of Regional Shift and Share [PDF]

open access: yes
This paper tests for cointegration between regional output of an industry and national output of the same industry. An equilibrium economic theory is presented to argue for the plausibility of cointegration, however, regional economic forecasting using ...
N. Edward Coulson   +2 more
core  

Home - About - Disclaimer - Privacy