Results 151 to 160 of about 624,139 (310)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Tax Competition and Profit Shifting: On the Relationship between Personal and Corporate Tax Rates [PDF]

open access: yes
The residence-based taxation of interest income in the EU faces the difficulty that taxpayers may evade taxation by holding bank accounts in other countries.
Clemens Fuest, Alfons Weichenrieder
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Shifting landscapes in-between times

open access: yes, 2013
“Shifting landscapes in-between times” addresses the fundamental relationship of landscape architecture to time. Jacky Bowring and Simon Swaffield focus on the devastating 2011 earthquakes in Christchurch, New Zealand to highlight the “enigma of design ...
Bowring, Jacqueline, Swaffield, SR
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Shifting Dusts

open access: yes, 2017
Description (included in portfolio of 2 solo exhibitions + Seasonal, Inter-State and others)\ud \ud Shifting Dusts was featured in The Mesh (2017) – the lead, curated visual arts exhibition of the internationally-renowned Vrystaat Kunstefees Arts ...
Armstrong, Keith M.   +2 more
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Shape-shifting slime

open access: yes, 2012
In this experiment a polystyrene cup is dissolved in acetone and remoulded into something newEnsino Fundamental Final::Ciências NaturaisEnsino Fundamental::Séries Iniciais::Ciências ...
Science Museum
core   +1 more source

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