Results 131 to 140 of about 4,742,454 (347)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Night shifts [PDF]

British Dental Journal, 2019
K, Patel, N, Adam, C, Mannion
openaire   +2 more sources

Shifting the genomic gold standard for the prokaryotic species definition

Proceedings of the National Academy of Sciences of the United States of America, 2009
Michael Richter, R. Rosselló-Móra
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Asymmetric Capital Tax Competition with Profit Shifting [PDF]

This paper analyses capital tax competition between jurisdictions of different size when multinational firms can shift some fraction of their tax base between them.
Stöwhase, Sven
core  

Shift Change

Annals of Emergency Medicine, 1998
[Parkhurst DC: Shift change. Ann Emerg Med June 1998;31:785-788.].
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Shifting the limits in wheat research and breeding using a fully annotated reference genome

Science, 2018
R. Appels, K. Eversole, N. Stein, C. Feuillet, B. Keller, J. Rogers, C. Pozniak, F. Choulet, A. Distelfeld, J. Poland, G. Ronen, A. Sharpe, Omer Barad, Kobi Baruch, G. Keeble-Gagnère, M. Mascher, Gil Ben-Zvi, A. Josselin, A. Himmelbach, F. Balfourier, Juan J. Gutierrez-Gonzalez, M. Hayden, C. Koh, G. Muehlbauer, R. Pasam, E. Paux, P. Rigault, J. Tibbits, V. Tiwari, M. Spannagl, D. Lang, H. Gundlach, G. Haberer, K. Mayer, D. Ormanbekova, Verena M. Prade, H. Šimková, T. Wicker, D. Swarbreck, Hélène Rimbert, Marius Felder, N. Guilhot, G. Kaithakottil, J. Keilwagen, P. Leroy, Thomas M. Lux, S. Twardziok, Luca Venturini, A. Juhász, M. Abrouk, I. Fischer, C. Uauy, P. Borrill, R. Ramirez-Gonzalez, D. Arnaud, Smahane Chalabi, B. Chalhoub, A. Cory, R. Datla, M. Davey, J. Jacobs, S. J. Robinson, B. Steuernagel, F. van Ex, B. Wulff, M. Benhamed, A. Bendahmane, L. Concia, D. Latrasse, J. Bartoš, A. Bellec, H. Bergès, J. Doležel, Z. Frenkel, B. Gill, A. Korol, T. Letellier, O. Olsen, Kuldeep Singh, M. Valárik, E. V. D. van der Vossen, S. Vautrin, S. Weining, T. Fahima, Vladimir Glikson, Dina Raats, J. Číhalíková, Helena Toegelová, J. Vrána, P. Sourdille, Benoît Darrier, D. Barabaschi, L. Cattivelli, P. Hernández, Sergio Gálvez, H. Budak, Jonathan D. G. Jones, Kamil Witek, Guotai Yu, I. Small, Joanna Melonek, Ruonan Zhou, T. Belova, K. Kanyuka, R. King, K. Nilsen, Sean Walkowiak, R. Cuthbert, R. Knox, Krystalee Wiebe, D. Xiang, A. Rohde, T. Golds, J. Čížková, B. A. Akpınar, Sezgi Biyiklioglu, Liangliang Gao, Amidou N'Daiye, M. Kubaláková, J. Šafář, Françoise Alfama, A. Adam-Blondon, Raphael Flores, Claire Guerche, M. Loaec, H. Quesneville, J. Condie, J. Ens, Ron Maclachlan, Yifang Tan, A. Alberti, J. Aury, V. Barbe, A. Couloux, C. Cruaud, K. Labadie, S. Mangenot, P. Wincker, G. Kaur, M. Luo, S. Sehgal, P. Chhuneja, O. Gupta, S. Jindal, Parampreet Kaur, Palvi Malik, Priti Sharma, B. Yadav, N. Singh, J. Khurana, Chanderkant Chaudhary, P. Khurana, Vinod Kumar, A. Mahato, S. Mathur, A. Sevanthi, N. Sharma, Ram Sewak Singh Tomar, K. Holušová, O. Plíhal, M. Clark, D. Heavens, George Kettleborough, Jonathan Wright, Barbora Balcárková, Yuqin Hu, E. Salina, N. Ravin, K. Skryabin, A. Beletsky, V. Kadnikov, A. Mardanov, Michail A. Nesterov, A. Rakitin, E. Sergeeva, H. Handa, H. Kanamori, S. Katagiri, F. Kobayashi, S. Nasuda, Tsuyoshi Tanaka, Jianzhon Wu, F. Cattonaro, Min Jiumeng, Karl G. Kugler, M. Pfeifer, S. Sandve, Xu Xun, Bujie Zhan, J. Batley, P. Bayer, D. Edwards, S. Hayashi, Zuzana Tulpová, Paul Visendi, Licao Cui, Xianghong Du, Kewei Feng, Xiaojun Nie, W. Tong, Le Wang   +200 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Timing Canada: The Shifting Politics of Time in Canadian Literary Culture by Paul Huebener [PDF]

, 2016
Review of Paul Huebener\u27s Timing Canada: The Shifting Politics of Time in Canadian Literary ...
Lousley, Cheryl
core   +1 more source