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Pathogenesis of Shiga-Toxin Producing Escherichia coli

2011
Shiga toxin (Stx)-producing Escherichia coli (STEC) are food-borne pathogens that cause hemorrhagic colitis and a serious sequela, the hemolytic uremic syndrome (HUS). The largest outbreaks of STEC are due to a single E. coli serotype, O157:H7, although non-O157 serotypes also cause the same diseases.
Angela, Melton-Celsa   +3 more
openaire   +2 more sources

Treatment of Shiga Toxin–Producing Escherichia coli Infections

Infectious Disease Clinics of North America, 2013
The management of Shiga toxin-producing Escherichia coli (STEC) infections is reviewed. Certain management practices optimize the likelihood of good outcomes, such as avoidance of antibiotics during the pre-hemolytic uremic syndrome phase, admission to hospital, and vigorous intravenous volume expansion using isotonic fluids.
T Keefe, Davis   +3 more
openaire   +2 more sources

Treatment Strategies for Infections With Shiga Toxin-Producing Escherichia coli [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Infections with Shiga toxin-producing Escherichia coli (STEC) cause outbreaks of severe diarrheal disease in children and the elderly around the world. The severe complications associated with toxin production and release range from bloody diarrhea and hemorrhagic colitis to hemolytic-uremic syndrome, kidney failure, and neurological issues. As the use
Sabrina Mühlen, Petra Dersch
exaly   +4 more sources

Prevalence of Shiga toxin-producing Escherichia coli in beef

Meat Science, 2005
Over the past two decades, many human illness outbreaks were attributed to consumption of undercooked beef products containing Shiga toxin-producing Escherichia coli (STEC). The illnesses included mild or bloody diarrhea, hemorrhagic colitis, and the life-threatening hemolytic uremic syndrome (HUS).
H S, Hussein, L M, Bollinger
openaire   +2 more sources

Non-O157 Shiga-toxin-producing Escherichia coli

The Lancet Infectious Diseases, 2012
12 www.thelancet.com/infection Vol 12 January 2012 4 Bettelheim KA, Faiers M, Shooter RA. Serotypes of Escherichia coli in normal stools. Lancet 1972; 300: 1224–26. 5 Pennington H. Escherichia coli O104, Germany 2011. Lancet Infect Dis 2011; 11: 652–53. The full investigation of outbreaks is essential to understand their causes.
openaire   +2 more sources

Enterohemorrhagic (Shiga Toxin-Producing) Escherichia coli

2016
Enterohemorrhagic (Shiga toxin-producing) Escherichia coli (EHEC/STEC) is a zoonotic food- and waterborne pathogen that can cause human infections ranging from asymptomatic carriage or mild diarrhea to hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS).
Marta Rivas   +2 more
openaire   +1 more source

Epidemiology and diagnosis of Shiga toxin-producing Escherichia coli infections

Diagnostic Microbiology and Infectious Disease, 1999
Shiga toxin-producing Escherichia coli (STEC) have been identified as a worldwide cause of serious human gastrointestinal disease and the life-threatening hemolytic uremic syndrome. The most common serotype implicated is E. coli O157: H7, but infections involving various non-O157 serotypes have been found with increasing frequency in many countries ...
H, Karch   +3 more
openaire   +2 more sources

Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections

Current Opinion in Gastroenterology, 2008
Shiga toxin-producing Escherichia coli cause hemorrhagic colitis and hemolytic uremic syndrome. We will summarize the literature on incidence and outcomes of these infections, and then review the pathogenesis to explain the current recommendations against antibiotic use and to suggest alternative therapies.Shiga toxin-producing E.
Antonio, Serna, Edgar C, Boedeker
openaire   +2 more sources

A PCR–ELISA for detecting Shiga toxin-producing Escherichia coli

Microbes and Infection, 2002
A sensitive and specific PCR-ELISA was developed to detect Escherichia coli O157:H7 and other Shiga toxin-producing E. coli (STEC) in food. The assay was based on the incorporation of digoxigenin-labeled dUTP and a biotin-labeled primer specific for Shiga toxin genes during PCR amplification.
Beilei, Ge   +3 more
openaire   +2 more sources

Epidemiology of Argentinean Shiga Toxin-Producing Escherichia coli

2014
Shiga toxin-producing Escherichia coli (STEC) is an important food-borne pathogen that can cause nonbloody diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome(HUS). The first isolation of shiga toxin-producing Escherichia coli (STEC) O157 from cattle occurred in Argentina in 1977, when three E. coli O157 strains were recovered from feces of 13
Rivas, Marta   +5 more
openaire   +2 more sources

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