Results 1 to 10 of about 17,681 (220)

Identification of vaccine and drug targets in Shigella dysenteriae sd197 using reverse vaccinology approach [PDF]

Scientific Reports, 2022
Shigellosis is characterized as diarrheal disease that causes a high mortality rate especially in children, elderly and immunocompromised patients. More recently, the World Health Organization advised safe vaccine designing against shigellosis due to the
Khurshid Jalal, Tareq Abu-Izneid, Kanwal Khan, Muhammad Abbas, Ajmal Hayat, Sami Bawazeer, Reaz Uddin   +6 more
doaj   +2 more sources

Sibling sRNA RyfA1 Influences Shigella dysenteriae Pathogenesis. [PDF]

Genes (Basel), 2017
Small regulatory RNAs (sRNAs) of Shigella dysenteriae and other pathogens are vital for the regulation of virulence-associated genes and processes. Here, we characterize RyfA1, one member of a sibling pair of sRNAs produced by S. dysenteriae. Unlike its nearly identical sibling molecule, RyfA2, predicted to be encoded almost exclusively by non ...
Fris ME, Broach WH, Klim SE, Coschigano PW, Carroll RK, Caswell CC, Murphy ER.   +6 more
europepmc   +5 more sources

Synergistic efficacy of phage Henu10 with antibiotics against Shigella dysenteriae with insight into phage resistance and fitness trade-offs [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionThe irrational use of antibiotics has facilitated the emergence of multidrug- resistant Shigella spp., undermining the effectiveness of the currently available antibiotics. Consequently, there is an urgent need to explore new approaches, with
Jing Zhao, Baohong Chen, Weizhen Wang, Yu Kang, Erli Hu, Yuan Zhang, Huiling Chen, Xiao Xu, Xinying Ji, Xinying Ji, Yuhan Wang, Yuhan Wang, Tieshan Teng, Tieshan Teng, Salwa E. Gomaa, Salwa E. Gomaa, Salwa E. Gomaa   +16 more
doaj   +2 more sources

Whole genome data sequence for VIT_AJPSC phage against Shigella dysenteriae [PDF]

BMC Research Notes
Objective Antibiotic resistance is one of the major causes of the increase in bacterial infections worldwilde. This is why it is the need of an hour to look for an alternative treatment; bacteriophage therapy is one of the most potent.
Aishwarya Srivastava, N. S. Jayaprakash
doaj   +2 more sources

Shigella dysenteriae Serotype 1, Kolkata, India

Emerging Infectious Diseases, 2003
Since July 2002, bacteriologically confirmed shigellosis cases have increased, and multidrug-resistant Shigella dysenteriae serotype 1 strains have reemerged in patients hospitalized with diarrhea in Kolkata, India. The isolated strains of S. dysenteriae
Shanta Dutta, Dharitri Dutta, Phalguni Dutta, Shigeru Matsushita, Sujit Kumar Bhattacharya, Shin-ichi Yoshida   +5 more
doaj   +3 more sources

Production of egg yolk antibody (IgY) against a chimeric protein containing IpaD, StxB, and TolC antigens from Shigella: An investigation of its prophylactic effects against Shiga toxin (Stx) and Shigella dysenteriae in vitro and in vivo [PDF]

Heliyon
Shigella is a major problem in developing countries. Immunoglobulin Y (IgY) can be used for prophylaxis and neutralize bacteria. The aim of this study was to produce IgY against the chimeric protein containing IpaD, StxB, and TolC antigens from Shigella,
Nahal Hadi, Shahram Nazarian, Saber Rouhi, Seyed Edris Hosseini, Javad Fathi   +4 more
doaj   +2 more sources

An integrated in-silico approach for drug target identification in human pathogen Shigella dysenteriae. [PDF]

PLoS ONE
Shigella dysenteriae, is a Gram-negative bacterium that emerged as the second most significant cause of bacillary dysentery. Antibiotic treatment is vital in lowering Shigella infection rates, yet the growing global resistance to broad-spectrum ...
Hurria Qureshi, Amina Basheer, Wasim Sajjad, Muhammad Faheem, Syed Babar Jamal   +4 more
doaj   +2 more sources

Up-regulation of MUC2 and IL-1β expression in human colonic epithelial cells by Shigella and its interaction with mucins. [PDF]

PLoS ONE, 2011
BackgroundThe entire gastrointestinal tract is protected by a mucous layer, which contains complex glycoproteins called mucins. MUC2 is one such mucin that protects the colonic mucosa from invading microbes.
Radhakrishnan Prakash, Subramaniya Bharathi Raja, Halagowder Devaraj, Sivasitambaram Niranjali Devaraj   +3 more
doaj   +1 more source

Persistence factors and antibiotic susceptibility of enterobacteria isolated from various animal species [PDF]

BIO Web of Conferences, 2022
During the study, we isolated 575 strains of enterobacteria from various animal species belonging to the genus Escherichia, Shigella, Salmonella, Klebsiella, Proteus, Providencia, Hafnia, Morganella, Enterobacter, Citrobacter, Serratia, Erwinia, Kluyvera,
Ermakov Vladimir, Titov Nikolai
doaj   +1 more source

Preliminary Investigations on the Therapeutic Efficacy and Safety of Mixed Probiotic Lactic Acid Bacteria on Albino Rats Challenged with Shigella dysenteriae

Advanced Gut & Microbiome Research, 2023
This study investigates the potential of lactic acid bacteria (LAB) from the Nigerian beverage “kunun zaki” as alternative therapeutic agents against Shigella dysenteriae infections.
Adaeze Ngozi Ibejekwe, John Otumala Egbere, Michael Macvren Dashen, Anayochukwu Chibuike Ngene, Shawon Fredrick Akpagher, Joshua Ayobami Adetunji, Michael Eshioramhe Paul, Steve Kunle Oyero, Francis C. Udeozor, Yusuf A. Agabi, Pauline Ikpa   +10 more
doaj   +1 more source