Results 51 to 60 of about 54,989 (228)

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network

Tropical Medicine &International Health, EarlyView.
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva, Anthony Sifuna, Francis Orata, Caroline Omolo, Jacob Stanley Iramiot, Mark C. Enright, Awelani Mutshembele, Jian Zhou, William A. Shivoga   +8 more
wiley   +1 more source

Antimicrobial and Cytotoxic Activities of Biogenic Nanoparticles Produced by Cyanobacteria

ChemBioChem, Volume 27, Issue 5, 13 March 2026.
The article reviews the green synthesis of biogenic nanoparticles produced by cyanobacteria, highlighting their antimicrobial and cytotoxic properties. These nanoparticles, formed intra‐ or extracellularly, show activity against Gram‐positive and Gram‐negative bacteria as well as fungi and can induce apoptosis in tumor cells.
Laíne Santos Ribeiro, Rhuana Valdetário Médice, Janaína Morone Bavini, Camila Manoel Crnkovic, Samuel Cavalcante do Amaral   +4 more
wiley   +1 more source

Shigella OspC3 suppresses murine cytosolic LPS sensing

iScience, 2021
Summary: Shigella flexneri, a cytosol-invasive gram-negative pathogen, deploys an array of type III-secreted effector proteins to evade host cell defenses.
Changhoon Oh, Ambika Verma, Mohib Hafeez, Brandon Hogland, Youssef Aachoui   +4 more
doaj   +1 more source

Dihydromyricetin Regulates PANoptosis to Protect Salmonella Typhimurium‐Infected Weaned Piglets

Food Frontiers, Volume 7, Issue 2, March 2026.
After DHM pretreatment, piglets were subjected to Salmonella infection. Serum and ileocecal samples from the piglets were collected for TUNEL assay, Western blotting analysis, and metabolomics analysis. The results collectively indicated that DHM could protect piglets from Salmonella infection.
Tingting Xiao, Xinyi Tian, YiKun Li, Jie Zhang, Hongcan Huang, Yu‐Xuan Lyu, Baichuan Deng   +6 more
wiley   +1 more source

Bacteriophage Therapy Testing Against Shigella flexneri in a Novel Human Intestinal Organoid-Derived Infection Model

Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2019
Objective: Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been hindered by antibiotic resistance, a
Alejandro Llanos-Chea, Robert J. Citorik, Kourtney P. Nickerson, L. Ingano, G. Serena, Stefania Senger, T. Lu, A. Fasano, Christina S. Faherty   +8 more
semanticscholar   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Antibiotic resistance and serotype distribution of Shigella strains in Bangladesh over the period of 2014–2022: evidence from a nationwide hospital-based surveillance for cholera and other diarrheal diseases

Microbiology Spectrum
The objective of this study was to assess the prevalence, antimicrobial resistance patterns, and risk factors linked to Shigella infections through a nationwide hospital-based diarrheal disease surveillance in Bangladesh.
Mokibul Hassan Afrad, Md. Taufiqul Islam, Yasmin Ara Begum, Md. Saifullah, Faisal Ahmmed, Zahid Hasan Khan, Zakir Hossain Habib, Ahmed Nawsher Alam, Tahmina Shirin, Taufiqur Rahman Bhuiyan, Edward T. Ryan, Ashraful Islam Khan, Firdausi Qadri   +12 more
doaj   +1 more source

Development, Interlaboratory Evaluations, and Application of a Simple, High-Throughput Shigella Serum Bactericidal Assay

mSphere, 2018
Shigella is an important cause of diarrhea worldwide, with serotypes Shigella flexneri 2a, S. flexneri 3a, and Shigella sonnei demonstrating epidemiological prevalence.
Moon H. Nahm, Jigui Yu, Hailey P. Weerts, Heather Wenzel, Chitradevi S. Tamilselvi, Lakshmi Chandrasekaran, Marcela F. Pasetti, Sachin Mani, Robert W. Kaminski   +8 more
doaj   +1 more source

Vaginal‐Derived Potential Probiotics and Their Postbiotics Alleviate Aerobic Vaginitis via Suppressing TLR4/MyD88/NF‐κB Signalling Pathway and Potentially Enhancing Vaginal Barrier

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
Consolidated diagram of the mechanism by which L. crispatus YBR‐01, L. plantarum YBR‐01, and their postbiotics improve AV progression. ABSTRACT Antibiotic therapy is currently challenged by drug resistance and high recurrence in aerobic vaginitis (AV), making it urgent to seek novel strategies. In this study, we selected two potential probiotic strains
Meiyun Tian, Xinyi Zhang, Xuan Xu, Xia He, Xiaoyun Wu, Jing Wei, Buzhen Tan, Tingtao Chen   +7 more
wiley   +1 more source

Antimicrobial resistance patterns and prevalence of class 1 and 2 integrons in Shigella flexneri and Shigella sonnei isolated in Uzbekistan

Gut Pathogens, 2010
Background Shigella is a frequent cause of bacterial dysentery in the developing world. Treatment with effective antibiotics is recommended for shigellosis, but options become limited due to globally emerging resistance.
Madiyarov Ruslan S, Bektemirov Amir M, Ibadova Gulnara A, Abdukhalilova Gulnara K, Khodiev Aybek V, Bodhidatta Ladaporn, Sethabutr Orntipa, Mason Carl J   +7 more
doaj   +1 more source