Results 51 to 60 of about 40,170 (206)

Steps for Shigella Gatekeeper MxiC Function in Hierarchical Type III Secretion Regulation [PDF]

, 2017
Type III secretion systems are complex nanomachines used for injection of proteins from Gram-negative bacteria into eukaryotic cells. Although they are assembled when the environmental conditions are appropriate, they only start secreting upon contact ...
Blocker, Ariel J, Bordignon, Enrica, Da-kang, Shen, Liu, Xia, Martinez-Argudo, Isabel, Mode, Selma, Murillo, Isabel, Pain, Maria, Roehrich, A Dorothea, Sessions, Richard B   +9 more
core   +6 more sources

Antibiotic resistance and serotype distribution of Shigella strains in Bangladesh over the period of 2014–2022: evidence from a nationwide hospital-based surveillance for cholera and other diarrheal diseases

Microbiology Spectrum
The objective of this study was to assess the prevalence, antimicrobial resistance patterns, and risk factors linked to Shigella infections through a nationwide hospital-based diarrheal disease surveillance in Bangladesh.
Mokibul Hassan Afrad, Md. Taufiqul Islam, Yasmin Ara Begum, Md. Saifullah, Faisal Ahmmed, Zahid Hasan Khan, Zakir Hossain Habib, Ahmed Nawsher Alam, Tahmina Shirin, Taufiqur Rahman Bhuiyan, Edward T. Ryan, Ashraful Islam Khan, Firdausi Qadri   +12 more
doaj   +1 more source

Development, Interlaboratory Evaluations, and Application of a Simple, High-Throughput Shigella Serum Bactericidal Assay

mSphere, 2018
Shigella is an important cause of diarrhea worldwide, with serotypes Shigella flexneri 2a, S. flexneri 3a, and Shigella sonnei demonstrating epidemiological prevalence.
Moon H. Nahm, Jigui Yu, Hailey P. Weerts, Heather Wenzel, Chitradevi S. Tamilselvi, Lakshmi Chandrasekaran, Marcela F. Pasetti, Sachin Mani, Robert W. Kaminski   +8 more
doaj   +1 more source

Prevalence of Plasmid-Mediated Determinants With Decreased Susceptibility to Azithromycin Among Shigella Isolates in Anhui, China

Frontiers in Microbiology, 2020
ObjectiveThe aims of this study were to describe azithromycin (AZM) susceptibility patterns among Shigella isolates in Anhui, China and identify predictors of resistance with mobile element-mediated genes.MethodsA total of 517 non-duplicate Shigella ...
Yanyan Liu, Yanyan Liu, Yanyan Liu, Hongru Li, Na Lv, Yalong Zhang, Xihai Xu, Ying Ye, Ying Ye, Ying Ye, Yufeng Gao, Yufeng Gao, Yufeng Gao, Jiabin Li, Jiabin Li, Jiabin Li, Jiabin Li   +16 more
doaj   +1 more source

Targets for the MalI repressor at the divergent Escherichia coliK-12malX-malI promoters [PDF]

, 2010
Random mutagenesis has been used to identify the target DNA sites for the MalI repressor at the divergent Escherichia coli K-12 malX-malI promoters. The malX promoter is repressed by MalI binding to a DNA site located from position -24 to position -9 ...
Barnard, Barne, Busby, Chaudhuri, Clausen, El-Robh, Georgina S. Lloyd, Hollands, Jacob, Lloyd, Lodge, Mitchell, Mitchell, Reidl, Reidl, Rita E. Godfrey, Rojo, Stephen J.W. Busby, Swint-Kruse, Valentin-Hansen, Weickert, West, Zdych   +22 more
core   +1 more source

Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 235-244, January 2026.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu, Rachael M. Harrower, Ziang Li, Angela C. Brown   +3 more
wiley   +1 more source

Antimicrobial resistance patterns and prevalence of class 1 and 2 integrons in Shigella flexneri and Shigella sonnei isolated in Uzbekistan

Gut Pathogens, 2010
Background Shigella is a frequent cause of bacterial dysentery in the developing world. Treatment with effective antibiotics is recommended for shigellosis, but options become limited due to globally emerging resistance.
Madiyarov Ruslan S, Bektemirov Amir M, Ibadova Gulnara A, Abdukhalilova Gulnara K, Khodiev Aybek V, Bodhidatta Ladaporn, Sethabutr Orntipa, Mason Carl J   +7 more
doaj   +1 more source

Identification of Shiga-Toxin-Producing Shigella Infections in Travel and Non-Travel Related Cases in Alberta, Canada

Toxins, 2021
It has long been accepted that Shiga toxin (Stx) only exists in Shigella dysenteriae serotype 1. However, in recent decades, the presence of Shiga toxin genes (stx) in other Shigella spp. have been reported. We screened 366 Shigella flexneri strains from
Shuai Zhi, Brendon D. Parsons, Jonas Szelewicki, Yue T. K. Yuen, Patrick Fach, Sabine Delannoy, Vincent Li, Christina Ferrato, Stephen B. Freedman, Bonita E. Lee, Xiao-Li Pang, Linda Chui   +11 more
doaj   +1 more source

Exploiting Lactic Acid Bacteria for Regulating Autophagy to Improve Health in Foods and Supplements: A Recent Update

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Lactic acid bacteria (LAB) are frequently used as health supplements. They enhance digestion, regulate immunity, improve gut microbiota, and prevent and manage diseases. Autophagy has a crucial role in the prevention and treatment of tumors, cardiovascular diseases, and pathogenic infections.
Yang Chen, Fangyi Chen, Mengchen Li, Junfeng Xiao, Yang Mu, Chao Wang, Lusha Xia, Mingye Peng, Mengzhou Zhou   +8 more
wiley   +1 more source

Genomic insights into Shigella species isolated from small ruminants and manure in the North West Province, South Africa

Applied Microbiology and Biotechnology
This study investigated Shigella species’ antibiotic resistance patterns and genomic characteristics from small ruminants and manure collected in Potchefstroom, North West, South Africa. Whole genome sequencing was used to determine resistome profiles of
Tshepang Motlhaping, Tsepo Ramatla, Oriel Thekisoe, Ntelekwane George Khasapane, Kgaugelo E. Lekota   +4 more
doaj   +1 more source