Results 81 to 90 of about 39,545 (207)

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 23, September 8, 2025.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

Kemampuan Antibakteri Susu Fermentasi terhadap Escherichia coli dan Shigella

open access: yesJurnal Agripet, 2017
ABSTRAK. Penelitian ini dilakukan dengan menggunakan starter Lactobacillus plantarum pada konsentrasi 3%, 4% dan 5% dan diinkubasi selama 48 jam pada suhu kamar. Pengamatan terhadap susu fermentasi dilakukan selama 8 hari.
Zuraida Hanum   +2 more
doaj   +1 more source

Molecular Modeling of the Shigella flexneri Serogroup 3 and 5 O-Antigens and Conformational Relationships for a Vaccine Containing Serotypes 2a and 3a

open access: yesVaccines, 2020
The pathogenic bacterium Shigella flexneri is a leading global cause of diarrheal disease. The O-antigen is the primary vaccine target and distinguishes the 30 serotypes reported. Except for serotype 6, all S.
Jason Hlozek   +3 more
doaj   +1 more source

Uji Aktivitas Antibakteri Ekstrak Etanol Kulit Buah Langsat (Lansium Domesticum Cor.) Terhadap Shigella Flexneri [PDF]

open access: yes, 2013
Background: Diarrhea remains a health problem in developingcountries such as Indonesia. Poor environmental sanitation and thelack of clean water sources lead to this disease.
Sepdahlia, F. (Fransiska)
core   +1 more source

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 9, September 2025.
ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Asja Garling   +4 more
wiley   +1 more source

Comparative genome analysis of 15 clinical Shigella flexneri strains regarding virulence and antibiotic resistance

open access: yesAIMS Microbiology, 2019
Shigellosis is the major cause of dysentery globally. It is mainly attributed to two Shigella species, Shigella sonnei and Shigella flexneri, which leads to approximately 165 million infections and 1.1 million deaths each year.
Liang Wang   +6 more
doaj   +1 more source

Mitochondria mediate septin cage assembly to promote autophagy of Shigella [PDF]

open access: yes, 2016
Septins, cytoskeletal proteins with well-characterised roles in cytokinesis, form cage-like structures around cytosolic Shigella flexneri and promote their targeting to autophagosomes.
Buranyi, S   +13 more
core  

Targets for the MalI repressor at the divergent Escherichia coliK-12malX-malI promoters [PDF]

open access: yes, 2010
Random mutagenesis has been used to identify the target DNA sites for the MalI repressor at the divergent Escherichia coli K-12 malX-malI promoters. The malX promoter is repressed by MalI binding to a DNA site located from position -24 to position -9 ...
Barnard   +22 more
core   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

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