Results 31 to 40 of about 75,960 (314)

A compendium of Caenorhabditis elegans regulatory transcription factors: a resource for mapping transcription regulatory networks [PDF]

, 2005
Background Transcription regulatory networks are composed of interactions between transcription factors and their target genes. Whereas unicellular networks have been studied extensively, metazoan transcription regulatory networks remain largely ...
Deplancke, B., Grove, C.A., Hope, I.A., Reece-Hoyes, J.S., Shingles, J., Walhout, J.M.   +5 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Recommendations for vaccination against shingles

Quality in Sport
Introduction and purpose: Shingles, or herpes zoster, is a painful condition caused by the reactivation of the varicella-zoster virus, the same virus responsible for chickenpox.
Zuzanna Wyleciał, Eliza Pyla, Wiktoria Zamachowska, Julia Ząber   +3 more
doaj   +1 more source

Use of Factory-Waste Shingles and Cement Kiln Dust to Enhance the Performance of Soil Used in Road Works

Advances in Civil Engineering, 2009
An experimental work was conducted to study the use of factory-waste roof shingles to enhance the properties of fine-grained soil used in road works.
Aly Ahmed, Medhat Shehata, Said Easa
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A critical appraisal of ‘Shingrix’, a novel herpes zoster subunit vaccine (HZ/Su or GSK1437173A) for varicella zoster virus

Human Vaccines & Immunotherapeutics, 2017
HZ/Su, branded as ‘Shingrix’, is one of the newest vaccines to be submitted for multi-national regulatory approval. It is targeted to prevent shingles, a global concern with aging populations. A live attenuated vaccine for shingles has been available for
Tehmina Bharucha, Damien Ming, Judith Breuer   +2 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Genetic variation in the HLA region is associated with susceptibility to herpes zoster. [PDF]

, 2015
Herpes zoster, commonly referred to as shingles, is caused by the varicella zoster virus (VZV). VZV initially manifests as chicken pox, most commonly in childhood, can remain asymptomatically latent in nerve tissues for many years and often re-emerges as
Armstrong, G, Baldwin, E, Borthwick, KM, Bottinger, E, Burt, A, Carlson, CS, Carrell, DS, Carroll, RJ, Comstock, BA, Crane, PK, Crawford, DC, Crosslin, DR, de Andrade, M, Denny, JC, Doheny, KF, Hanna, DS, Harley, JB, Hayes, MG, Jarvik, GP, Keating, B, Kho, A, Kim, DS, Kuivaniemi, H, Kullo, IJ, Larson, EB, Li, R, McCarty, CA, Mirel, DB, Mukherjee, S, Pacheco, J, Peissig, PL, Pugh, E, Ritchie, MD, Stallings, S, Tromp, G, Underwood, JG, Verma, SS   +36 more
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Using noun phrases extraction for the improvement of hybrid clustering with text- and citation-based components. The example of “Information Systems Research” [PDF]

, 2015
The hybrid clustering approach combining lexical and link-based similarities suffered for a long time from the different properties of the underlying networks.
Glänzel, Wolfgang, Meyer, Martin S., Thijs, Bart   +2 more
core