Results 41 to 50 of about 16,643 (237)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

True knowledge about shingles among responders.

open access: yes, 2019
Note: “Shingles can be caught from someone else who has shingles.” (Correct answer: false); “Shingles can lead to long-lasting, severe pain.” (Correct answer: true); “The chance of developing shingles increases with age.” (Correct answer: true ...
Nick Sevdalis (221168)   +7 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Shingles Case Study Competition

open access: yesSouth African Family Practice, 1993
No abstract available.
G.M. Cutler
doaj   +3 more sources

Shingles [PDF]

open access: yes, 2016
Millions of people in the United States are effected by shingles each year. Shingles, which is also known as herpes zoster, is caused by the reactivation of the varicella zoster virus. The varicella zoster virus is what causes chicken pox. After a person
Holland, Kimberly M
core  

GPs’ perceptions of shingles and the shingles vaccine (1 = strongly disagree, 7 = strongly agree).

open access: yes, 2019
GPs’ perceptions of shingles and the shingles vaccine (1 = strongly disagree, 7 = strongly agree).
Nick Sevdalis (221168)   +7 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Shingles and shingled roofs [PDF]

open access: yes, 1981
From the early medieval period and well into the nineteenth century, shingles were one of the main roofin materials used for prominet buildings in Swedish churches and belfries, castles and manor houses.
Tollestén, Kristin
core  

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