Results 31 to 40 of about 16,643 (237)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Postoperative Shingles Mimicking Recurrent Radiculopathy after Anterior Cervical Diskectomy and Fusion

open access: yesGlobal Spine Journal, 2015
Study Design Case report and review of literature. Objective To report the case of a 67-year-old woman who developed delayed onset (6 months) of symptomatic shingles after cervical nerve root decompression in a previously symptomatic dermatome.
Jason T. Montgomery   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

A nanoparticle vaccine displaying varicella-zoster virus gE antigen induces a superior cellular immune response than a licensed vaccine in mice and non-human primates

open access: yesFrontiers in Immunology
Herpes zoster (HZ), also known as shingles, remains a significant global health issue and most commonly seen in elderly individuals with an early exposure history to varicella-zoster virus (VZV).
Yuanyuan Li   +11 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Recommendations for vaccination against shingles [PDF]

open access: yes
Introduction and purpose: Shingles, or herpes zoster, is a painful condition caused by the reactivation of the varicella-zoster virus, the same virus responsible for chickenpox.
Zuzanna Wyleciał   +3 more
core   +3 more sources

Perceptions, knowledge and barriers: A survey of healthcare workers on shingles vaccination

open access: yesAnnals, Academy of Medicine, Singapore
In older adults, herpes zoster, also known as shingles, is a common infectious disease. The estimated lifetime risk of shingles in the general population is about 30%;1 this increases to 50% at age 85 years old.2 Among the morbidities associated with ...
Jessica Weizhen Chen   +2 more
doaj   +1 more source

The analysis of risk factors for developing shingles

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2012
Shingles (herpes zoster) is caused by the reactivation of human herpes virus type 3 (HHV-3) that has been latent in the cranial nerves ganglion and dorsal root ganglion.
Paulina Gawrońska   +3 more
doaj   +1 more source

Buckling of Asphalt Shingles

open access: yes, 1956
In a recent report it has been shown that asphalt shingles are not dimensionally stable when exposed to conditions of wetting and drying. The dimensional instability of wood caused by changes in moisture content is well known.
Slade, H. F., Sereda, P. J.
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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