Results 41 to 50 of about 75,960 (314)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Frontiers in ImmunologyHerpes zoster (HZ), also known as shingles, remains a significant global health issue and most commonly seen in elderly individuals with an early exposure history to varicella-zoster virus (VZV).
Yuanyuan Li +11 more
doaj +1 more source
Scalable Techniques for Similarity Search [PDF]
, 2015 Document similarity is similar to the nearest neighbour problem and has applications in various domains. In order to determine the similarity / dissimilarity of the documents first they need to be converted into sets containing shingles. Each document is
Nagireddy, Siddartha Reddy
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Shingles Case Study Competition
South African Family Practice, 1993 No abstract available.
G.M. Cutler
doaj +3 more sources
Perceptions, knowledge and barriers: A survey of healthcare workers on shingles vaccination
Annals, Academy of Medicine, SingaporeIn older adults, herpes zoster, also known as shingles, is a common infectious disease. The estimated lifetime risk of shingles in the general population is about 30%;1 this increases to 50% at age 85 years old.2 Among the morbidities associated with ...
Jessica Weizhen Chen +2 more
doaj +1 more source
New materials for fireplace logs [PDF]
, 1971 Fibrous insulation and refractory concrete are used for logs as well as fireproof walls, incinerator bricks, planters, and roof shingles. Insulation is lighter and more shock resistant than fireclay.
Kieselback, D. J., Smock, A. W.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Shingles & Pneumococcal Vaccines: Recommendations for Older Adults [PDF]
, 2018 As the immune system tends to weaken over time, patients aged 50+ begin having increased risk for certain potentially preventable diseases, especially shingles and pneumonia.
Flinn, Benjamin
core +1 more source
High Percentages of Reclaimed Asphalt Affect the Performance of Asphalt Binder [PDF]
, 2020 More than 90 percent of the road and highway network in the United States is paved with asphalt concrete. Maintenance and periodic rehabilitation require a continuous supply of aggregates and asphalt binder, both of which are becoming increasingly scarce
Butt, Ali A. +2 more
core