Results 41 to 50 of about 78,541 (361)

Recombinant zoster vaccine in immunocompetent and immunocompromised adults: A review of clinical studies

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Herpes zoster (HZ) is a debilitating vaccine-preventable disease. Impairment of cell-mediated immunity, as observed with aging and immunosuppressive disorders and therapies, increases risk.
Agnes Mwakingwe-Omari   +4 more
doaj   +1 more source

Risk of Guillain-Barré syndrome following herpes zoster, United States, 2010–2018

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Epidemiologic data regarding the risk of Guillain-Barré syndrome (GBS) following herpes zoster (HZ) are limited. We conducted a self-controlled case series analysis using two large national data sources to evaluate the risk of GBS following HZ among U.S.
Tara C. Anderson   +3 more
doaj   +1 more source

Early examination of real-world uptake and second-dose completion of recombinant zoster vaccine in the United States from October 2017 to September 2019

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Shingrix (Recombinant zoster vaccine, RZV) was approved in October 2017 in the United States (US) for the prevention of herpes zoster in adults aged 50 years and older.
Brandon J. Patterson   +5 more
doaj   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

Shingrix: Educating Patients on the New Shingles Vaccine [PDF]

open access: yes, 2018
Herpes zoster (shingles) is a viral infection that results in a painful rash and has a myriad of long-term complications, including post-herpetic neuralgia- chronic pain that does not resolved despite resolution of the rash.
Jost, Sarah Natasha
core   +1 more source

Recommendations for vaccination against shingles

open access: yesQuality in Sport
Introduction and purpose: Shingles, or herpes zoster, is a painful condition caused by the reactivation of the varicella-zoster virus, the same virus responsible for chickenpox.
Zuzanna Wyleciał   +3 more
doaj   +1 more source

A critical appraisal of ‘Shingrix’, a novel herpes zoster subunit vaccine (HZ/Su or GSK1437173A) for varicella zoster virus

open access: yesHuman Vaccines & Immunotherapeutics, 2017
HZ/Su, branded as ‘Shingrix’, is one of the newest vaccines to be submitted for multi-national regulatory approval. It is targeted to prevent shingles, a global concern with aging populations. A live attenuated vaccine for shingles has been available for
Tehmina Bharucha   +2 more
doaj   +1 more source

Potential public health impact of the adjuvanted recombinant zoster vaccine among people aged 50 years and older in Beijing

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Herpes zoster (HZ) is a painful, unilateral rash which occurs upon reactivation of latent varicella zoster virus due to age-related immunity decline or immuno-suppression. In 2019, the recombinant zoster vaccine (RZV) was the first vaccine to be approved
Christa Lee   +5 more
doaj   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Genetic variation in the HLA region is associated with susceptibility to herpes zoster. [PDF]

open access: yes, 2015
Herpes zoster, commonly referred to as shingles, is caused by the varicella zoster virus (VZV). VZV initially manifests as chicken pox, most commonly in childhood, can remain asymptomatically latent in nerve tissues for many years and often re-emerges as
Armstrong, G   +36 more
core  

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