Results 61 to 70 of about 74,771 (264)

The far-ultraviolet spectra of two hot PG1159 stars

open access: yes, 2016
PG1159 stars are hot, hydrogen-deficient (pre-) white dwarfs with atmospheres mainly composed of helium, carbon, and oxygen. The unusual surface chemistry is the result of a late helium-shell flash.
Kruk, J. W., Rauch, T., Werner, K.
core   +1 more source

More than shingles [PDF]

open access: yesClinical Kidney Journal, 2012
A 66-year-old man who had end-stage renal disease and was undergoing maintenance hemodialysis presented with facial edema together with a strip of blisters and crust over the right side of his reddened forehead. Initially, the symptoms seemed indicative of herpes zoster ophthalmicus. However, his left periorbital area was more swollen than the infected
Neild, G. H.   +4 more
openaire   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The Baptist Church in Warren: Rehabilitation and Preservation Report [PDF]

open access: yes, 2013
The Baptist Church in Warren is located in the Warren Waterfront Historic National Register District. Warren also has a Voluntary Historic District. Both the National Register Nomination and the Voluntary Historic District have regulations which pertain ...
Bambara, Lauren   +4 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Suitability of Wooden Shingles for Ventilated Roofs: An Evaluation of Ventilation Efficiency

open access: yesApplied Sciences, 2020
Wooden shingles are a traditional roofing material on many culturally important building artifacts. Currently, the roof space of many traditional buildings is used for residential purposes and, consequently, cold roof constructions with ventilation ...
Günther Kain   +4 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Herpes zoster (Shingles)

open access: yesSouth African Family Practice, 2018
Herpes zoster or Shingles is caused by varicella-zoster virus (VZV), the same virus that causes chicken-pox (varicella). Primary infection with varicella-zoster virus causes chicken-pox (varicella), then the virus persists in nerve ganglia of sensory but
M. H. Motswaledi
doaj   +1 more source

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