Results 51 to 60 of about 2,195 (197)

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Herpes Zoster in Hematological Disorders: Pathogenesis, Risk Stratification, and Emerging Strategies for Prevention and Immunization

European Journal of Haematology, Volume 116, Issue 1, Page 14-22, January 2026.
ABSTRACT Background Herpes zoster (HZ), resulting from reactivation of latent varicella‐zoster virus (VZV), imposes a significant burden on immunocompromised patients, particularly those with hematological malignancies and recipients of hematopoietic stem cell transplants (HSCT).
Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Santino Caserta, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

A nanoparticle vaccine displaying varicella-zoster virus gE antigen induces a superior cellular immune response than a licensed vaccine in mice and non-human primates

Frontiers in Immunology
Herpes zoster (HZ), also known as shingles, remains a significant global health issue and most commonly seen in elderly individuals with an early exposure history to varicella-zoster virus (VZV).
Yuanyuan Li, Siyu Tian, Yuanbao Ai, Zhulong Hu, Chao Ma, Meijuan Fu, Zhenqian Xu, Yan Li, Shuyun Liu, Yongjuan Zou, Yu Zhou, Jing Jin   +11 more
doaj   +1 more source

Adjuvant Effects of a New Saponin Analog VSA-1 on Enhancing Homologous and Heterosubtypic Protection by Influenza Virus Vaccination

Vaccines, 2022
Adjuvants can increase the magnitude and durability of the immune response generated by the vaccine antigen. Aluminum salts (Alum) remain the main adjuvant licensed for human use. A few new adjuvants have been licensed for use in human vaccines since the
Noopur Bhatnagar, Ki-Hye Kim, Jeeva Subbiah, Bo Ryoung Park, Pengfei Wang, Harvinder Singh Gill, Bao-Zhong Wang, Sang-Moo Kang   +7 more
doaj   +1 more source

Patient Education on the Shingrix Vaccine [PDF]

, 2018
The CDC recommends that most adults over the age of 50 get the Shingrix vaccine for protection against shingles (herpes zoster). Many patients at the WCHN Southbury Primary Care clinic in Connecticut are eligible for vaccination but are unaware of this ...
Patel, Arjun
core   +1 more source

Recombinant Zoster Vaccine Associated with a Reduced Risk of Dementia Onset among US Beneficiaries ≥65 Years of Age

Alzheimer's &Dementia, Volume 21, Issue S7, December 2025.
Abstract Background Research showing lower risk of all‐cause dementia, Alzheimer’s Disease (AD), and vascular dementia (VD) with herpes zoster vaccination was based on one vaccine no longer marketed in the US. We evaluated the risk of dementia among US Medicare beneficiaries ≥65 years‐old who received recombinant zoster vaccine (RZV) relative to ...
Susan dosReis, Phuong Tran, Kareshma Mohanty, Alejandro Amill‐Rosario, Abree Johnson, Kathleen Ryan, Hannah Alsdurf, Driss Oraichi, Sofia B Pinto, Huifeng Yun   +9 more
wiley   +1 more source

Repurposing anti-viral subunit and mRNA vaccines T cell immunity for intratumoral immunotherapy against solid tumors

npj Vaccines
Intratumoral (IT) immunotherapy can stimulate the tumor microenvironment and enhance anti-tumor immunity. We investigated IT delivery of three licensed viral vaccines—Shingrix (VZV shingles), Gardasil-9 (HPV), and Spikevax (SARS-CoV-2)—in prevaccinated ...
Shiv K. Sethi, Claire E. Bradley, Lukas Bialkowski, Yuk Ying Pang, Cynthia D. Thompson, John T. Schiller, Nicolas Çuburu   +6 more
doaj   +1 more source

Herpes zoster mRNA vaccine induces superior vaccine immunity over licensed vaccine in mice and rhesus macaques

Emerging Microbes and Infections
Herpes zoster remains an important global health issue and mainly occurs in aged and immunocompromised individuals with an early exposure history to Varicella Zoster Virus (VZV).
Lulu Huang, Tongyi Zhao, Weijun Zhao, Andong Shao, Huajun Zhao, Wenxuan Ma, Yingfei Gong, Xianhuan Zeng, Changzhen Weng, Lingling Bu, Zhenhua Di, Shiyu Sun, Qinsheng Dai, Minhui Sun, Limei Wang, Zhenguang Liu, Leilei Shi, Jiesen Hu, Shentong Fang, Cheng Zhang, Jian Zhang, Guan Wang, Karin Loré, Yong Yang, Ang Lin   +24 more
doaj   +1 more source

Reactivation of Herpes Zoster After Recombinant Vaccine (Shingrix): A Case Report

Cureus, 2023
Herpes zoster (HZ) is a common contagious dermatological condition that results from reactivation of varicella-zoster virus (VZV), which currently could be prevented by vaccination. We describe a rare case of varicella infection reactivation after routine zoster vaccination in an immunocompetent female in her 60s who developed dermatomal pruritic and ...
Altukhaim, Feras, Mutlaq, May, Alghamdi, Mohammed, Hakami, Salha   +3 more
openaire   +2 more sources

Clinical progress note: Varicella Zoster

Journal of Hospital Medicine, Volume 20, Issue 12, Page 1348-1350, December 2025.
Abstract Varicella Zoster virus (VZV) is the etiologic agent responsible for varicella and herpes zoster (shingles). Nonimmune children and adults acutely infected with VZV typically experience a vesicular and pruritic rash that progresses from the face and trunk and generalizes to the extremities, accompanied by an oral enanthem along with symptoms of
Sirey Zhang, Adam L. Hersh, T. W. Jones
wiley   +1 more source