Results 121 to 130 of about 27,286 (356)

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

A RANS Modelling Approach for Predicting Powering Performance of Ships in Waves

open access: yes, 2013
In this paper, a modelling technique for simulating selfpropelled ships in waves is presented. The flow is modelledusing a RANS solver coupled with an actuator diskmodel for the propeller.
Hudson, Dominic   +7 more
core   +1 more source

ANALISA DEVINISI KAPAL IKAN PURSE SEINE 109 GT KM. SURYA REDJEKI

open access: yesKapal, 2012
Traditional ship has so many kinds, It can be seen on every beach in Indonesia which has different ship design.this development ship design changes based on the ancestors' experiences and the miths believed by the society.
Ari Wibawa BS
doaj  

How do secondary schools in England talk about modern languages? A corpus‐assisted discourse analysis of school websites

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Situating the study within an ecological perspective on language education, this article examines how secondary schools in England present Modern Languages (MLs) on official school websites. Focusing on 44 schools in Local Authorities with the lowest percentage average entry for the Languages pillar of the EBacc, we built a text database ...
Zhu Hua, Yunpeng Du, Elin Arfon
wiley   +1 more source

Added wave resistance prediction and comparative study based on point cloud feature extraction

open access: yesZhongguo Jianchuan Yanjiu
ObjectiveIn order to rapidly forecast added wave resistance in the ship design stage, this paper proposes a neural network based on point cloud feature extraction.
Mingfeng WU, Renchuan ZHU, Dekang XU
doaj   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner   +7 more
wiley   +1 more source

Model scale investigation of aspects influencing the ice resistance of ships sailing ahead in level ice

open access: yes, 2020
For a reliable prediction of the total resistance in ice in an early ship design stage, it is of great importance to have knowledge on the different influencing aspects.
Myland, Daniela, Ehlers, Sören
core  

Race-time prediction for the Va’a paralympic sprint canoe

open access: yes, 2014
The 2016 Paralympic Games in Rio de Janeiro will see 200m sprint canoe events for the first time, using the Va’a class. The aim of this study is to predict race times for the Va’a over a 200m sprint event, through simulation of the hydrodynamic ...
Crossley, H.C.   +3 more
core   +1 more source

The effect of appendages on ship resistance

open access: diamond, 2021
Andreea Mandru, Florin Pacuraru
openalex   +1 more source

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