Results 131 to 140 of about 73,774 (266)

Amazon in the Arctic: E-Commerce, Infrastructure, and Alimentary Assemblages in Nunavut, Canada. [PDF]

J Contemp Ethnogr
Schmid K.
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

ISCCO: a deep learning feature extraction-based strategy framework for dynamic minimization of supply chain transportation cost losses. [PDF]

PeerJ Comput Sci
Li Y, Chen T.
europepmc   +1 more source

Can we use hedonic pricing to estimate freight value of time? [PDF]

In this article, we investigate the use of hedonic pricing method to measure freight value of time. We concentrate on the demand side of the freight market (that is shippers) and give a pre-cise definition to transport duration.
Jérôme Massiani
core  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Impact of smart energy on a three-echelon closed-loop supply chain management with reduction of carbon emissions. [PDF]

Sci Rep
Bar N, Sangal I, Sarkar B.
europepmc   +1 more source

Special report No 2/87. The quality of food aid. The extent to which food aid products comply with the applicable rules as regards quality, quantity, packaging, time and place together with the Commission's replies. Official Journal C 219, 17 August 1987 [PDF]

, 1987

core  

Cargo/Logistics Airlift System Study (CLASS), Executive Summary [PDF]

The current air cargo system is analyzed along with advanced air cargo systems studies. A forecast of advanced air cargo system demand is presented with cost estimates.
Henderson, R. D., Macey, F. C., Norman, J. M., Tuttle, R. P.   +3 more
core   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Challenges in radiopharmaceutical importation across six Southern African Development Community countries: an exploratory study. [PDF]

Front Med (Lausanne)
Mkhombo VG, Mosima L, Summers B.
europepmc   +1 more source