Results 151 to 160 of about 73,774 (266)

Enhance triangular fuzzy parametric framework for solid multi objective transportation problem with split decision variables. [PDF]

Sci Rep
Joshi VD, Sharma M, Čepová L, Alsaud H, Kalita K.   +4 more
europepmc   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

Increasing load factor in logistics and evaluating shipment performance with machine learning methods: A case from the automotive industry. [PDF]

Sci Rep
Kılıç Sarıgül R, Erkayman B, Usanmaz B.   +2 more
europepmc   +1 more source

Environment and economic analysis of reverse supply chain scenarios for remanufacturing using discrete-event simulation approach. [PDF]

Environ Dev Sustain, 2023
Ravichandran M, Vimal KEK, Kumar V, Kulkarni O, Govindaswamy S, Kandasamy J.   +5 more
europepmc   +1 more source

NUP85 Mediates Endoplasmic Reticulum Stress through the USP47/ASK1 Signaling Pathway to Regulate the Progression of Liver Fibrosis

Advanced Science, EarlyView.
In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang, Haoran Yang, Linxin Pan, Chang Tian, Fucheng Zuo, Shilei Huang, Xianrui Li, Ming Chen, Cheng Qian, Jie Wang, Zhaolin Chen, Tao Xu   +11 more
wiley   +1 more source

Generative AI and Blockchain-Integrated Multi-Agent Framework for Resilient and Sustainable Fruit Cold-Chain Logistics. [PDF]

Foods
Khanna A, Jain S, Sah A, Dangi S, Sharma A, Tiang SS, Wong CH, Lim WH.   +7 more
europepmc   +1 more source

Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor

Advanced Science, EarlyView.
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang, Yixiang Deng, Nan Xia, Shuzo Sugita, Shangbang Gao   +4 more
wiley   +1 more source

Supplying Relief: Civil Medical Assistance during the Korean War, 1950-3. [PDF]

Soc Hist Med
Lee D, Harrison M.
europepmc   +2 more sources

Adverse commercial determinants of health in low- and middle-income countries: a public health challenge. [PDF]

Health Promot Int
Islam MM, De Lacy-Vawdon C, Gleeson D.
europepmc   +1 more source