Results 111 to 120 of about 57,342 (256)

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Biomarkers in cardiogenic shock: old pals, new friends

Annals of Intensive Care
In cardiogenic shock, biomarkers should ideally help make the diagnosis, choose the right therapeutic options and monitor the patient in addition to clinical and echocardiographic indices.
Mathieu Jozwiak, Sung Yoon Lim, Xiang Si, Xavier Monnet   +3 more
doaj   +1 more source

The Danish Out‐of‐Hospital Cardiac Arrest Trial: A Statistical Analysis Plan

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Post‐cardiac arrest care for patients resuscitated from out‐of‐hospital cardiac arrest (OHCA) includes multiple pharmacological and physiological interventions, yet optimal strategies to reduce post‐cardiac arrest syndrome–related morbidity and mortality remain uncertain.
Simon Mølstrøm, Jacob E. Møller, Henrik Schmidt, Anders M. Grejs, Steffen Christensen, Jesper Kjærgaard, Christian Hassager, Martin A. S. Meyer, Lars P. K. Andersen, Bodil S. Rasmussen, Jo B. Andreasen, Sören Möller   +11 more
wiley   +1 more source

Inpatient Outcomes and Complications After Left Atrial Appendage Occlusion in Rural Versus Urban Hospitals in the United States

Clinical Cardiology, Volume 49, Issue 7, July 2026.
A majority of Left atrial appendage occlusion (LAAO) implantations occurred in urban hospitals. Urban patients had higher rates of overall, major, and pulmonary complications, as well as more discharges to home than rural patients in unadjusted analysis.
Amanda Nguyen, Muhammad Zia Khan, Joseph Neely, Waleed Alruwaili, Muhammad Abdullah Naveed, Justin Lim Devera, William E. Leon, Siddharth Agarwal, Zain Ul Abideen Asad, Samrina Khan, Karthik Gonuguntla, Daniel Ice, Muhammad Bilal Munir   +12 more
wiley   +1 more source

Mortality of women with ST-segment elevation myocardial infarction and cardiogenic shock – results from the PL-ACS registry

, 2016
Introduction: Gender-related differences are well elucidated in ST-segment elevation myocardial infarction (STEMI) patients. However, data on patients with cardiogenic shock (CS) are scarce and do not indicate the cause-effect relationship.
Mariusz Gąsior, Małgorzata Kołodziej, Marek Gierlotka, Jacek Kurzawski, Agnieszka Janion-Sadowska, Marcin Sadowski, Lech Poloński   +6 more
core   +1 more source

Population Pharmacokinetics of Ticagrelor during Veno‐Arterial ECMO in Acute Coronary Syndrome: Model‐Informed Dosing Simulations

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 193-202, July 2026.
Although patients with acute coronary syndrome supported by veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) have a high risk of thrombosis and bleeding, antiplatelet pharmacology in this setting is not well defined. This prospective observational study investigated the population pharmacokinetics of ticagrelor and its active metabolite AR ...
Soyoung Kang, Kyoung Lok Min, Seungwon Yang, Jongsung Hahn, Dasohm Kim, Byung Hak Jin, Soon Uk Chae, Soo Kyung Bae, Jin Wi, Min Jung Chang   +9 more
wiley   +1 more source

Efficacy and safety of microaxial flow pump in infarct-related cardiogenic shock: a meta-analysis

Introduction Data regarding mechanical circulatory support with a microaxial flow pump (Impella) in patients with myocardial infarction complicated by cardiogenic shock are limited.
Ayesha Javed, Rafia Hussain, Raheel Ahmed, Mushood Ahmed, Mudassar Baig, Farhan Shahid, Muhammad Hamza Nasim, Muhammad Ayyan, Saad Ur Rahman, Mfonobong Umoh, Muhammad Umar Liaqat, Aeman Waqar, Hanzalah Bin Arshad, Saad Javed, Saira Bano, Komal Fatima   +15 more
core   +1 more source

Cognitive Functioning After Circulatory Shock: A Prospective Observational Study

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Cognitive impairment in intensive care unit (ICU) survivors is multifactorial and can affect especially memory, attention, and executive functions. This study aimed to determine the cognitive functioning of patients with circulatory shock immediately after ICU discharge and 3 months later.
Salla Laurila, Eva Nordenswan, Henriikka Ollila, Riikka Pihlaja, Erika Wilkman, Elina Varis, Maria Heliste, Sanna Koskinen, Annamari Tuulio‐Henriksson, Marjaana Tiainen, Heini Huhtala, Anne H. Kuitunen, Laura Hokkanen, Johanna Hästbacka   +13 more
wiley   +1 more source

Remifentanil Versus Rocuronium for Optimising Video Laryngoscopy Assisted Tracheal Intubation—The ROCVIDEO Trial Protocol

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Routine use of neuromuscular blocking agents (NMBAs) is widely recommended to facilitate tracheal intubation. However, NMBA use is associated with potential adverse effects, including postoperative respiratory complications, intraoperative awareness and anaphylaxis.
Emil Ørskov Ipsen, Lars Hyldborg Lundstrøm, Åse Lodenius, Gustav Fisker, Magnus Fuhr Hovind, Christian Lindgren Nielsen, Hrund Oskarsdottir, Camilla Strøm, Charlotte Vallentin Rosenstock, Karl Peter Damgård Madsen, Sine Wichmann, Arash Afshari, Jacob Hessel Andersen, Helene Korvenius Nedergaard, Louise Bill, Maria Cronhjort, Ole Mathiesen, Janus Christian Jakobsen, Matias Vested, Anders Kehlet Nørskov   +19 more
wiley   +1 more source

Platelet Transfusion Is Associated With Increased Thrombosis and In‐Hospital Mortality Among Patients Hospitalized With Platelet Consumptive Disorders

European Journal of Haematology, Volume 117, Issue 1, Page 245-257, July 2026.
ABSTRACT Background Platelet transfusion is commonly used to reduce bleeding risk in platelet consumptive disorders. However, platelets may also promote thromboinflammatory pathways, and contemporary data evaluating the association between platelet transfusion, thrombosis, and mortality in this population are limited.
Manas Pustake, Shubhangi Deoker, Veeravenkata Garikiparthy, Kunal Sharma, Lakshmi Kattamuri, Abhizith Deoker, Abhinav Deol   +6 more
wiley   +1 more source