Results 121 to 130 of about 57,342 (256)

Intra-aortic balloon pump in cardiogenic shock: state of the art

open access: yesRevista do Colégio Brasileiro de Cirurgiões
The clinical definition of cardiogenic shock is that of a low cardiac output and evidence of tissue hypoxia in the presence of adequate blood volume.
PETRONIO GENEROSO THOMAZ   +3 more
doaj   +1 more source

Inflammatory Stewardship—A Perspective for Active Management of Acute Inflammation

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Inflammatory stewardship frames inflammation as a manageable clinical domain requiring explicit strategy, governance, and feedback. It aligns diagnostics, risk stratification, biomarker interpretation, and immunomodulatory decisions across perioperative and critical‐care teams.
Lennart Finn Herrlich   +2 more
wiley   +1 more source

Detection of MSI signals from peripheral blood for monitoring response to immune checkpoint blockade therapy in patients with advanced microsatellite‐unstable gastrointestinal cancers: A pilot study

open access: yesInternational Journal of Cancer, Volume 158, Issue 12, Page 3312-3323, 15 June 2026.
What's new? A substantial proportion of patients with microsatellite‐unstable gastrointestinal adenocarcinomas do not benefit from immunotherapy. This study demonstrates that microsatellite instability can be reliably detected in plasma‐derived extracellular vesicle DNA from patients with microsatellite‐unstable gastrointestinal cancers.
Aysel Ahadova   +16 more
wiley   +1 more source

Cardiogenic Shock [PDF]

open access: yes, 1968
80% of people developing shock after myocardial infarction die. This essay is concerned to ask why they die and what can be done about it.Accordingly it consists of two parts: the one concerned with the definition and some relevant aspects of the ...
Leitch, Andrew Gordon
core  

Successful Revascularization of Chronic Total Occlusions in Patients With Chronic Thromboembolic Pulmonary Disease

open access: yesCatheterization and Cardiovascular Interventions, Volume 107, Issue 7, Page 2323-2334, June 1, 2026.
ABSTRACT Background Chronic thromboembolic pulmonary disease (CTEPD) leads to chronic total occlusions (CTOs) of the pulmonary arteries in a minority of patients. Treatment of CTOs with balloon pulmonary angioplasty (BPA) may substantially improve patient hemodynamics but presents unique technical challenges and has previously been associated with a ...
Elliot J. Stein   +4 more
wiley   +1 more source

Long QT Syndrome Type 5 With Coexisting KCNE1 and RYR2 Variants: A Diagnostic Ambiguity

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Long QT syndrome (LQTS) predisposes to syncope and sudden cardiac death. Type 5 LQTS, linked to KCNE1 variants, is rare. A teenage female presented with recurrent syncope. ECG showed QTc 485 ms. Genetic testing identified KCNE1 and RYR2 variants. Beta‐blockers and ICD prevented events.
Mohammad Hossein Nikoo   +4 more
wiley   +1 more source

Severe Lactic Acidosis in Decompensated Cirrhosis Despite Nondiagnostic Imaging

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Lactic acidosis is a strong predictor of mortality in cirrhosis, reflecting both impaired hepatic clearance and systemic tissue hypoxia. We describe a 38‐year‐old man with decompensated alcohol‐associated cirrhosis who developed severe lactic acidosis despite stable hemodynamics and initially nondiagnostic vascular imaging.
Nakul Ganju   +5 more
wiley   +1 more source

Autopsy‐Proven Immune‐Mediated Hepatitis With Rapid Liver Atrophy Despite Minimal Aminotransferase Elevation After Durvalumab Plus Tremelimumab Therapy for Hepatocellular Carcinoma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Immune‐mediated hepatitis caused by immune checkpoint inhibitors (ICIs) is typically suspected based on aminotransferase elevation; however, biochemical signals may be blunted in advanced cirrhosis, potentially delaying recognition. A 71‐year‐old woman with cirrhosis due to metabolic dysfunction–associated steatohepatitis and Barcelona Clinic ...
Hidenobu Hara   +17 more
wiley   +1 more source

Trametinib Therapy for Hypertrophic Cardiomyopathy and Pulmonary Hypertension in a Child With RAF1‐Related Noonan Syndrome (p.Ser257Leu): A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case describes a female infant with RAF1‐related Noonan syndrome who developed severe hypertrophic obstructive cardiomyopathy, pulmonary hypertension, and cardiorespiratory failure that responded to trametinib treatment but ultimately progressed to death following dose tapering and discontinuation of therapy. To the best of our knowledge,
C. Noah Nilsson   +8 more
wiley   +1 more source

Mechanical circulatory support in patients in cardiogenenic shock

open access: yesСучасні медичні технології
Cardiogenic shock in acute myocardial infarction is a life-threatening syndrome characterized by systemic hypoperfusion that can rapidly progress to multiple organ failure and death.
V. H. Tanskyi
doaj   +1 more source

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