Results 31 to 40 of about 91,505 (268)

The effect of subdiaphragmatic vagotomy on heart rate variability and lung inflammation in rats with severe hemorrhagic shock

BMC Cardiovascular Disorders, 2022
Background The influence of cutting the sub-diaphragmatic branch of the vagus nerve on heart rate variability (HRV) and inflammatory reaction to severe hemorrhagic shock has not been determined prior to this study.
Fateme Khodadadi, Farzaneh Ketabchi, Zahra Khodabandeh, Alireza Tavassoli, Gregory F. Lewis, Aminollah Bahaoddini   +5 more
doaj   +1 more source

Class of hemorrhagic shock is associated with progressive diastolic coronary flow reversal and diminished left ventricular function

Frontiers in Physiology, 2022
Introduction: The relationship between coronary artery flow and left ventricular (LV) function during hemorrhagic shock remains unknown. The aim of this study was to quantify coronary artery flow directionality alongside left ventricular function through
Noha N. Elansary, Noha N. Elansary, David P. Stonko, Rebecca N. Treffalls, Hossam Abdou, Marta J. Madurska, Jonathan J. Morrison   +6 more
doaj   +1 more source

Impaired Fracture Healing after Hemorrhagic Shock

Mediators of Inflammation, 2015
Impaired fracture healing can occur in severely injured patients with hemorrhagic shock due to decreased soft tissue perfusion after trauma. We investigated the effects of fracture healing in a standardized pressure controlled hemorrhagic shock model in ...
Philipp Lichte, Philipp Kobbe, Roman Pfeifer, Graeme C. Campbell, Rainer Beckmann, Mersedeh Tohidnezhad, Christian Bergmann, Mamed Kadyrov, Horst Fischer, Christian C. Glüer, Frank Hildebrand, Hans-Christoph Pape, Thomas Pufe   +12 more
doaj   +1 more source

Centhaquine Restores Renal Blood Flow and Protects Tissue Damage After Hemorrhagic Shock and Renal Ischemia

Frontiers in Pharmacology, 2021
Background: Centhaquine (CQ) (Lyfaquin®) is in late stage clinical development as a safe and effective first-in-class resuscitative agent for hemorrhagic shock patients (NCT02408731, NCT04056065, and NCT04045327). Acute kidney injury (AKI) is known to be
Amaresh K. Ranjan, Zhong Zhang, Seema Briyal, Anil Gulati, Anil Gulati   +4 more
doaj   +1 more source

C-Jun N-terminal kinase 2 promotes liver injury via the mitochondrial permeability transition after hemorrhage and resuscitation [PDF]

, 2012
Hemorrhagic shock leads to hepatic hypoperfusion and activation of mitogen-activated stress kinases (MAPK) like c-Jun N-terminal kinase (JNK) 1 and 2. Our aim was to determine whether mitochondrial dysfunction leading to hepatic necrosis and apoptosis ...
Czerny, Christoph, Lehnert, Mark, Lemasters, John J., Maldonado, Eduardo N., Marzi, Ingo, Theruvath, Tom Prakash, Zhong, Zhi   +6 more
core   +2 more sources

Is I-FABP not only a marker for the detection abdominal injury but also of hemorrhagic shock in severely injured trauma patients?

World Journal of Emergency Surgery, 2019
Background Hemorrhagic shock can lead to intestinal damage with subsequent hyperinflammation and multiple organ dysfunction syndrome (MODS). The intestinal fatty acid-binding protein (I-FABP) is solely expressed in the intestine and is released ...
Maika Voth, Thomas Lustenberger, Borna Relja, Ingo Marzi   +3 more
doaj   +1 more source

Experimental Models of Hemorrhagic Shock: A Review [PDF]

, 2013
Massive blood loss leading to hypovolemic shock is still a life-threatening situation. Recently, a great number of investigations have been conducted in order to understand the pathophysiological and immunological changes taking place during shock and to
Fülöp András, Garbaisz Dávid, Harsányi László, Szijártó Attila, Turóczi Zsolt   +4 more
core   +1 more source

Replacing the Transfusion of 1-2 Units of Blood with Plasma Expanders that Increase Oxygen Delivery Capacity: Evidence from Experimental Studies. [PDF]

, 2014
At least a third of the blood supply in the world is used to transfuse 1-2 units of packed red blood cells for each intervention and most clinical trials of blood substitutes have been carried out at this level of oxygen carrying capacity (OCC ...
Acharya, Seetharama A, Cabrales, Pedro, Intaglietta, Marcos, Kistler, Erik B, Salazar Vázquez, Beatriz Y, Subramaniam, Shankar, Tartakovsky, Daniel M, Tsai, Amy G   +7 more
core   +3 more sources

Preperitoneal pelvic packing as a salvage operation for postoperative retroperitoneal bleeding with hemodynamic instability after the Kocher-Langenbeck approach to the acetabulum: a case report [PDF]

Journal of Trauma and Injury
Pelvic fractures result from high-energy trauma, and when accompanied by hemorrhagic shock, the mortality rate increases to 40%. Pelvic fractures are anatomically categorized as pelvic ring disruptions and acetabular fractures, each requiring different ...
Doo-Hun Kim, Maru Kim, Dae-Sang Lee, Tae Hwa Hong, Hangjoo Cho   +4 more
doaj   +1 more source

Vertebral Heart Score: A Useful Parameter in Determination of Resuscitation Endpoint in Dogs with Hemorrhagic Shock [PDF]

Iranian Journal of Veterinary Medicine, 2019
BACKGROUND: GReliable prediction of patient response to fluid resuscitation is a crucial issue in the management of hemorrhagic shock. OBJECTIVES: This study was designed to investigate vertebral heart score (VHS) variation in fluid resuscitation of ...
Reza Azargoun, Reza Avizeh, Alireza Ghadiri, Hadi Imani Rastabi, Mahdi Pourmahdi   +4 more
doaj   +1 more source