Results 111 to 120 of about 610,317 (302)
Advanced Science, EarlyView.NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source
Função e reatividade cardíaca in situ na sepse em ratos: diferenças entre gêneros e modelos experimentais [PDF]
, 2014 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.A sepse representa a principal causa de mortes em unidades de terapia intensiva. A disfunção cardíaca
Gonçalves, Ronald Paiva Moreno
core
Different patterns of Siglec-9-mediated neutrophil death responses in septic shock
, 2009 Sialic-acid-binding immunoglobulin-like lectin (Siglec) 9 mediates death signals in neutrophils. The objective of this study was to determine the heterogeneity of neutrophil death responses in septic shock patients and to analyze whether these ex vivo ...
Simon, Hans-Uwe +4 more
core +1 more source
Septic shock by gram-negative infections: role of outer membrane proteins [PDF]
, 2012 The magnitude of septic shock as a clinical problem is often understated. Despite advances in our ability to diagnose and treat infectious diseases, severe sepsis leading to shock due to gram-negative infections remains one of the leading causes of ...
TARALLO, ROSSELLA +9 more
core +1 more source
Advanced Science, EarlyView.A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang +12 more
wiley +1 more source
Kidney & Blood Pressure Research, 2019 Background: Septic shock, the most serious complication of sepsis, is a life-threatening disease that is mainly characterized by hypoperfusion and multiple organ failure. Various aberrantly expressed microRNAs (miRNAs) have been reported to be related to
Lan Ling +4 more
doaj +1 more source
The clinical features and surgical treatment of acute septic arthritis in Malawian children. [PDF]
, 2006 Introduction: Untreated and poorly treated septic arthritis in children is a major cause of orthopaedic pathology in Malawi and the rest of sub Saharan Africa, yet little has been published on its early treatment, or its incidence, clinical features and ...
Lavy, C.B.D.
core
Advanced Science, EarlyView.Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li +10 more
wiley +1 more source
Renin – angiotensin – aldosterone system in patients with septic shock (literature review)
Вестник анестезиологии и реаниматологииThe objective was to summarize current data on the role of renin-angiotensin-aldosterone system (RAAS) in patients with septic shock (SS) and to highlight indications for the use of Angiotensin II in the complex of intensive care of septic shock ...
L. L. Plotkin
doaj +1 more source
Advanced Science, EarlyView.Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan +13 more
wiley +1 more source