Results 41 to 50 of about 895,705 (294)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

A Shock-Capturing Algorithm for the Differential Equations of Dilation and Erosion [PDF]

open access: yesJournal of Mathematical Imaging and Vision, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Michael Breuß, Joachim Weickert
openaire   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Modelling and Forecasting Processes in Urban Environments: Particularly in the UK and China

open access: yesHydrology
The modelling and forecasting of the impact of extreme rainfall events in urban environments is becoming increasingly challenging as historical tools have been found to need refinement to acquire improved flood risk predictions for river and coastal ...
Roger Alexander Falconer
doaj   +1 more source

Numerical Modelling of Gas-Liquid Slug Flow Regime with a Conservative Two-Fluid Model Using the Shock Capturing Method [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering
An approach for simulating the initiation of slugs in horizontal pipes is proposed in this research. An analogy is established between the algorithms for solving single-phase problems with discontinuity (Riemann problems) and two-phase slug flow (having ...
Mohammad Hassan Yahyanezhad   +2 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Evaluating the Capability of the Flux-Limiter Schemes in Capturing Strong Shocks and Discontinuities

open access: yesShock and Vibration, 2013
A numerical study is conducted to investigate the capability of the flux-limiter TVD schemes in capturing sharp discontinuities like shock waves. For this purpose, four classical test problems are considered such as slowly moving shock, gas Riemann ...
Iman Harimi, Ahmad Reza Pishevar
doaj   +1 more source

A Simple and Robust Shock-Capturing Approach for Discontinuous Galerkin Discretizations

open access: yesEnergies, 2019
The discontinuous Galerkin (DG) method has become popular in Computational Fluid Dynamics mainly due to its ability to achieve high-order solution accuracy on arbitrary grids, its high arithmetic intensity (measured as the ratio of the number of floating
Jae Hwan Choi   +2 more
doaj   +1 more source

Development of an unsteady shock-fitting technique for unstructured grids

open access: yes, 2017
A novel, unstructured, shock-fitting algorithm capable of simulating unsteady flows has recently being developed. The capabilities of this novel unstructured shock-fitting technique are here tested by reference to the inviscid interaction between a ...
Valentina De Amicis   +9 more
core   +1 more source

Improving the quantification of overshooting shock-capturing oscillations [PDF]

open access: yes, 2023
An approach for quantitatively evaluating overshooting oscillations is designed to characterize the performance of shock-capturing schemes. Specifically, following our previous work focused on cases with only discontinuities, now we account for the ...
Zhang, Fan
core   +1 more source

Home - About - Disclaimer - Privacy