Results 181 to 190 of about 1,009,891 (343)

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Medical anti-shock trousers (pneumatic anti-shock garments) for circulatory support in patients with trauma

, 1999
Ian Roberts, Karen Blackhall, Karen J. Dickinson   +2 more
openalex   +2 more sources

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Mechanical circulatory support for refractory cardiogenic shock post-acute myocardial infarction—a decade of lessons [PDF]

, 2019
Sanjeet Singh, Sudeep Das De, Francesco Nappi, Ahmed Al‐Adhami, Yasser Hegazy, Jonathan R. Dalzell, Harikrishna Doshi, Andrew Sinclair, Philip Curry, Mark C. Petrie, Colin Berry, Nawwar Al‐Attar   +11 more
openalex   +1 more source

Predicting mortality in cardiogenic shock secondary to ACS requiring short‐term mechanical circulatory support: The ACS‐MCS score

, 2021
Qussay Marashly, Iosif Taleb, Christos P. Kyriakopoulos, Elizabeth Dranow, Tara L. Jones, Anwar Tandar, Sean Overton, Joseph E. Tonna, Kathleen Stoddard, Omar Wever‐Pinzon, Line Kemeyou, Antigone Koliopoulou, Kevin Shah, Kimiya Nourian, Tyler J. Richins, Tyson Burnham, Frederick G.P. Welt, Stephen H. McKellar, José Nativi-Nicolau, Stavros G. Drakos   +19 more
openalex   +2 more sources

Temporary circulatory support for cardiogenic shock

The Lancet, 2020
A. Combes, S. Price, A. Slutsky, D. Brodie   +3 more
semanticscholar   +1 more source

Production and Formulation of Alcanivorax borkumensis SK2 Cell Powders for Marine Oil Spill Bioremediation

Biotechnology and Applied Biochemistry, EarlyView.
Abstract Oil spills pose severe threats to marine ecosystems and coastal communities. Alcanivorax borkumensis SK2, a marine bacterium with superior hydrocarbon‐degrading capabilities, emerges as a promising agent for bioremediation. This study identified an economical growth substrate for A.
Élisabeth Perreault, Denis Groleau, Patrick Vermette   +2 more
wiley   +1 more source

From cramming to binge‐watching: Integrating documentary‐based assessment into a pharmacology and toxicology curriculum—a qualitative study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims In the context of pharmacology and toxicology education, there is a growing shift toward programmatic assessment models that prioritize longitudinal learning, reflection and development of higher‐order cognitive skills. As part of this transition, we are exploring alternative and more meaningful forms of assessment. This qualitative study
Narin Akrawi, Heleen van der Sijs, Floor van Rosse   +2 more
wiley   +1 more source

Improving outcomes of patients with severe respiratory and circulatory failure following living donor liver transplantation: efficacy of extracorporeal membrane oxygenation. [PDF]

Hepatobiliary Surg Nutr
Soyama A, Sekino M, Hara T, Eguchi S.
europepmc   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source