Results 181 to 190 of about 908,035 (248)

Integrating Powder Metallurgy with Explosive Cladding: A Novel Route for Bimetallic Copper-Steel Tube Fabrication. [PDF]

Materials (Basel)
Błoniarz R, Zyguła K, Szymańczyk L, Hara M.   +3 more
europepmc   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

Delayed presentation of left-sided penetrating diaphragmatic injury with multivisceral herniation, gastric fundal perforation, and splenic laceration leading to fatal septic shock: a case report from Ethiopia. [PDF]

Int J Surg Case Rep
Oljira AM, Bikila BN, Hordofa DA, Beyene SG.   +3 more
europepmc   +1 more source

EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2‐Mediated µ‐Opioid Receptor Internalization

Advanced Science, EarlyView.
Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng, Xiaqing Lin, Hongyu Yao, Cheng Li, Huabao Liao, Yuexin Liu, Boxu Cao, Xue‑Jun Song   +7 more
wiley   +1 more source

Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut‐Liver Axis

Advanced Science, EarlyView.
Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji, Yan Fang, Shen Zhang, Weichen Xu, Wenyun Guo, Jing Chen, Mingrui Zhu, Congjian Wen, Siming Chen, Yuli Zhu, Huixiong Xu, Haohao Yin   +11 more
wiley   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

Advanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou, Jianing Jing, Zhuohan Shi, Lei Sun   +3 more
wiley   +1 more source

Ischemic Gastroduodenitis: Navigating the Challenges of Enteral Nutrition Resumption. [PDF]

ACG Case Rep J
Stasiewicz M, Naga Y, Ohning GV, Aponte-Pieras J.   +3 more
europepmc   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

Advanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu, Huaping Zhao, Lizhuang Chen, Weidong Shi, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source

Reproductive thermotolerance: from flower development to seed initiation. [PDF]

New Phytol
Chu JW, Chang S, Li HJ.
europepmc   +1 more source

Allium sativum, a Natural and Pharmaco‐Remedial Panacea for Entero‐Gastritis, Antibiocidal/Dysbiogenesis, and Systemic Health Relevance

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Natural Pharmaco‐remedial impacts of Allium sativum on Systemic health. ABSTRACT Arising from the emergence of diverse difficult‐to‐treat health cases, alterative‐therapeutic strategies have become a potential way forward for management/control. In traditional Chinese medicine (TCM), various plant materials have been sourced as alterative‐therapeutic ...
Patience O. Adomi, Bright E. Igere, Anthony J. Anozie, Oghenenyore A. Ohwokevwo   +3 more
wiley   +1 more source