Advanced Science, EarlyView.PTBP1‐mediated alternative splicing drives a pathogenic switch to the DNAJB6b isoform in everolimus‐resistant clear cell renal cell carcinoma. This splicing event programs a positive feedback loop including EIF4B/PKIB/AKT/mTOR, promoting aggressive therapy resistance.
Xiu‐wu Pan +18 more
wiley +1 more source
A shock-tube experimental and kinetic simulation study on the autoignition of methane at ultra-lean and lean conditions. [PDF]
HeliyonZhao Z +6 more
europepmc +1 more source
Effective testing of personal protective equipment in blast loading conditions in shock tube: Comparison of three different testing locations. [PDF]
PLoS One, 2018 Skotak M +4 more
europepmc +1 more source
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Advanced Science, EarlyView.Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source
On the formation of Friedlander waves in a compressed-gas-driven shock tube. [PDF]
Proc Math Phys Eng Sci, 2016 Tasissa AF +3 more
europepmc +1 more source
Youngstown Sheet and Tube Company's Campbell Works boiler house
, 1912 Refined waste gas is routed to the boiler house to be utilized as fuel to heat water for production of steam. After the boilers were installed, the building was constructed around them.
Youngstown Sheet and Tube Company
core
Advanced Science, EarlyView.A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song +6 more
wiley +1 more source
High-Speed Three-Dimensional-Digital Image Correlation and Schlieren Imaging Integrated With Shock Tube Loading for Investigating Dynamic Response of Human Tympanic Membrane Exposed to Blasts. [PDF]
J Eng Sci Med Diagn TherAlipanahi A +4 more
europepmc +1 more source
A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior
Advanced Science, EarlyView.Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li +12 more
wiley +1 more source
Geometry‐Encoded Soft Strain Sensing via Liquid‐Metal Transmission Lines
Advanced Science, EarlyView.This study presents a liquid‐metal transmission‐line strain sensor that achieves intrinsic decoupling by encoding axial elongation into propagation delay. The time‐domain readout remains stable under complex off‐axis. This enables reliable, repeatable, real‐time elongation measurement in dynamic, multiaxial loading environments for wearable electronics,
Zhang Liu +12 more
wiley +1 more source