Results 131 to 140 of about 1,831,047 (296)

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song   +6 more
wiley   +1 more source

Unsteadiness in shock-wave/boundary layer interactions

open access: yes, 2010
The need for better understanding of the low-frequency unsteadiness observed in shockwave/turbulent boundary layer interactions has been driving research in this area forseveral decades.
Touber, Emile
core   +1 more source

Geometry‐Encoded Soft Strain Sensing via Liquid‐Metal Transmission Lines

open access: yesAdvanced Science, EarlyView.
This study presents a liquid‐metal transmission‐line strain sensor that achieves intrinsic decoupling by encoding axial elongation into propagation delay. The time‐domain readout remains stable under complex off‐axis. This enables reliable, repeatable, real‐time elongation measurement in dynamic, multiaxial loading environments for wearable electronics,
Zhang Liu   +12 more
wiley   +1 more source

WEC Scale Model Build & Test: Fabrication and Wave Laboratory Testing of 1/10 Scale Wave Energy Conversion Device

open access: yes
Neptune Wave Power, LLC (‘NWP’), worked with OWET, the Northwest National Marine Renewable Energy Center (‘NNMREC’) and Oregon State University (O.H. Hinsdale Wave Research Laboratory) to build and test a 1/10 scale model wave energy conversion (‘WEC ...
Neptune Wave Power LLC   +1 more
core   +3 more sources

Flow instability in shock tube due to shock wave-boundary layer-contact surface interactions, a numerical study [PDF]

open access: yes, 2009
This paper describes numerical simulation of transient flow conditions in shock tube. A two dimensional time accurate Navier-Stokes CFD solver for shock tube applications is developed to perform the numerical investigations.
Yusaf, T.   +3 more
core  

Active Oscillations of Elastic Membranes Arising from the Coupling with a Catalytic Reaction

open access: yesAdvanced Science, EarlyView.
Coupling an elastic membrane to a catalytic reaction produces active oscillations that self‐sustain for hours: the membrane cyclically inflates and deflates as the reaction spontaneously activates and deactivates, without external power. Energy release is directly embodied in the oscillation dynamics, opening elasto‐chemical strategies for the physical
Alberto Comoretto   +5 more
wiley   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

open access: yesAdvanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han   +11 more
wiley   +1 more source

Influence of Temperature on Mechanical Properties and Spall Damage of Invar36 Alloy

open access: yesGaoya wuli xuebao
This study systematically investigated the effects of temperature on the spall behavior of Invar36 alloy through plate impact experiments and microstructural characterization techniques.
Zeming TANG   +3 more
doaj   +1 more source

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

open access: yesAdvanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang   +9 more
wiley   +1 more source

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