Results 41 to 50 of about 1,179,932 (361)
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
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I prezzi delle materie prime non petrolifere: comportamento ciclico e capacita informativa*
Moneta e Credito, 2013 The work proposes a survey of the empirical factors of the prices of non-oil commodities and the short-term determinants of their performance. In addition, it seeks to examine to what degree sudden changes of direction in the prices of commodities have ...
R. CARUSO
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Shock Equations and Jump Conditions for the 2D Adjoint Euler Equations
Aerospace, 2023 This paper considers the formulation of the adjoint problem in two dimensions when there are shocks in the flow solution. For typical cost functions, the adjoint variables are continuous at shocks, wherein they have to obey an internal boundary condition,
Carlos Lozano, Jorge Ponsin
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Prognostic value of soluble endoglin in patients with septic shock and severe COVID-19 [PDF]
, 2022 Veronika Tomášková +10 more
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FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
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The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
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Reflections on the impacts of the COVID-19 pandemic on rural livelihoods
Frontiers in Sustainable Food SystemsThe COVID-19 pandemic has had long-lasting impacts on agricultural development and rural society, increasing the uncertainty of the entire agricultural system and victimizing rural livelihoods.
Chuanxi Wang, Xiaobo Hua
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Social networks and ex post risk management among smallholder farmers in Kenya
Development Studies Research, 2019 Smallholder farmers in developing countries are vulnerable to idiosyncratic and covariate risks. The risks affect their welfare through the shocks they impose on income, assets, health and food supply.
Mercy Mbugua +2 more
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FEBS Open Bio, EarlyView.Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey +2 more
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