Results 41 to 50 of about 6,022,431 (243)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

A Rotor Winding Internal Short-Circuit Fault Protection Method for Variable-Speed Pumped Storage Units

open access: yesApplied Sciences, 2022
In electrical machinery, the rotor windings’ internal short-circuit faults are addressed by the instantaneous over-current protection of the power electronic excitation device, which has low sensitivity and has difficulty meeting the safety requirements.
Rufei He   +6 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Test System for Short Circuit Protection of Lithium Ion Storage Battery for Mine

open access: yesMeikuang Anquan, 2020
In this paper, the test system for short circuit protection of lithium ion storage battery is designed. The system is mainly composed of timing control unit and data analysis unit.
GUO Changna
doaj   +1 more source

Determination of Relay Opening Current Information and Coordination of Distribution Network of Sakarya Province, Yazlık Region

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2021
Electricity is delivered to end users through generation, transmission, and distribution phases. The most important issues during energy journey is to provide selective, rapid, and safe protection to ensure energy continuity.
Uğur Arifoğlu   +2 more
doaj   +1 more source

An Improved di/dt-RCD Detection for Short-Circuit Protection of SiC MOSFET [PDF]

open access: yes, 2021
Silicon Carbide (SiC) metal-oxide-semiconductor field-effect transistor (MOSFET) has a smaller short-circuit tolerance, and hence requires faster and more accurate short-circuit protection.
Loh, Poh Chiang   +4 more
core   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Design analysis of mine-used intrinsic safety power supply

open access: yesGong-kuang zidonghua, 2014
In view of requirements that intrinsic safety power supply must has multi-protection of over-current and over-voltage, the paper introduced working principle of a circuit of mine-used intrinsic safety power supply based on LM317 regulator, analyzed ...
LIU Qi
doaj   +1 more source

Investigation on safe-operating-area degradation and failure modes of SiC MOSFETs under repetitive short-circuit conditions

open access: yesPower Electronic Devices and Components, 2023
The safe operating area is an operating area with high reliability for SiC MOSFET, and its degradation may cause power electronic system failure. The safe-operating-area degradation and the failure modes of 1200 V/66A SiC MOSFET caused by repetitive ...
Ziyang Zhang, Lin Liang, Haoyang Fei
doaj   +1 more source

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