Results 21 to 30 of about 5,002,199 (254)
Cardio-Hypothalamic-Pituitary Coupling during Rest and in Response to Exercise
The objective of this study was to examine cardio hypothalamic-pituitary coupling and to better understand how the temporal relations between these systems are altered during rest and exercise conditions.
Nathaniel T. Berry +2 more
doaj +1 more source
Autonomic activity affects beat-to-beat variability of heart rate and QT interval. The aim of this study was to explore whether entropy measures are suitable to detect changes in neural outflow to the heart elicited by two different stress paradigms.
Mathias Baumert +5 more
doaj +1 more source
Inverse stochastic–dynamic models for high-resolution Greenland ice core records [PDF]
Proxy records from Greenland ice cores have been studied for several decades, yet many open questions remain regarding the climate variability encoded therein.
N. Boers +10 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The classical “R-on-T” phenomenon
The polymorphic ventricular tachycardia (PVT) is uncommon arrhythmia with multiple causes and has been classified according to whether they are associated with long QT interval or normal QT.
Fatih Oksuz +9 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The origin of slow intrinsic oscillations in resting states of functional magnetic resonance imaging (fMRI) signals is still a matter of debate. The present study aims to test the hypothesis that slow blood oxygenation level-dependent (BOLD) oscillations
Gert Pfurtscheller +8 more
doaj +1 more source
Vegetation response to a short interval between high-severity wildfires in a mixed-evergreen forest [PDF]
1 Variations in disturbance regime strongly influence ecosystem structure and function. A prominent form of such variation is when multiple high-severity wildfires occur in rapid succession (i.e. short-interval (SI) severe fires, or ‘re-burns’).
Kauffman, J.B. +4 more
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Kuniaki Otsuka,1,2 Shougo Murakami,3 Kiyotaka Okajima,4 Koichi Shibata,1 Yutaka Kubo,5 Denis G Gubin,6– 8 Larry A Beaty,2 Germaine Cornelissen2 1Tokyo Women’s Medical University, Tokyo, Japan; 2Halberg Chronobiology Center, University of Minnesota ...
Otsuka K +7 more
doaj

