Results 151 to 160 of about 308,842 (252)

Evaluation of PacBio Long-Read and PCR-Based Short-Read Sequencing for Mitochondrial DNA (mtDNA) Variant Detection, with an Emphasis on Detection and Quantification of mtDNA Deletion. [PDF]

Int J Mol Sci
Jadhav T, Aruta M, Diaz-Miranda MA, Zucco A, Conlin LK, Rajagopalan R, Wang J.   +6 more
europepmc   +1 more source

Combination of long-read and short-read sequencing provides comprehensive transcriptome and new insight for Chrysanthemum morifolium ray-floret colorization. [PDF]

Sci Rep, 2022
Kishi-Kaboshi M, Tanaka T, Sasaki K, Noda N, Aida R.   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Genotyping of selected germline adaptive immune system loci using short-read sequencing data. [PDF]

Genome Res
Ford MKB, Hari A, Yeager M, Mirabello L, Chanock S, Numanagić I, COVNET Consortium, Sahinalp SC.   +7 more
europepmc   +1 more source

Lessons learned: overcoming common challenges in reconstructing the SARS-CoV-2 genome from short-read sequencing data via CoVpipe2. [PDF]

F1000Res, 2023
Lataretu M, Drechsel O, Kmiecinski R, Trappe K, Hölzer M, Fuchs S.   +5 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Comparative Meta-Analysis of Long-Read and Short-Read Sequencing for Metagenomic Profiling of the Lower Respiratory Tract Infections. [PDF]

Microorganisms
Lorenzin G, Carlin M.
europepmc   +1 more source

A Benchmark of Genetic Variant Calling Pipelines Using Metagenomic Short-Read Sequencing. [PDF]

Front Genet, 2021
Andreu-Sánchez S, Chen L, Wang D, Augustijn HE, Zhernakova A, Fu J.   +5 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Structural variants in the barley gene pool: precision and sensitivity to detect them using short-read sequencing and their association with gene expression and phenotypic variation. [PDF]

Theor Appl Genet, 2022
Weisweiler M, Arlt C, Wu PY, Van Inghelandt D, Hartwig T, Stich B.   +5 more
europepmc   +1 more source