Results 41 to 50 of about 95,141 (307)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Short Term Load Forecasting Based Artificial Neural Network [PDF]

open access: yesIraqi Journal for Electrical and Electronic Engineering, 2014
Present study develops short term electric load forecasting using neural network; based on historical series of power demand the neural network chosen for this network is feed forward network, this neural network has five input variables ( hour of the ...
Adel M. Dakhil
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The short-term tsunami forecast

open access: yesIOP Conference Series: Earth and Environmental Science, 2021
Abstract A brief overview of the methods of a tsunami early warning in the Kuril Islands, which turned out to be ineffective during recent events, is presented. A hydrophysical method for short-term tsunami forecasting based on information about a tsunami in the ocean, used in the United States, and an express method, also using ...
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Integration of demand response and short-term forecasting for the management of prosumers' demand and generation [PDF]

open access: yes, 2019
The development of Short-Term Forecasting Techniques has a great importance for power system scheduling and managing. Therefore, many recent research papers have dealt with the proposal of new forecasting models searching for higher efficiency and ...
Gabaldón, Antonio [0000-0002-0952-4607]   +11 more
core   +1 more source

Weather Nowcasting and Short Term Forecasting

open access: yes, 2012
This article is about present weather and its immediate development, on the challenge of how to observe it, and how to forecast it in the short term. It touches on the problems meteorologists have in delivering reliable estimates of, e.g., which path a thunderstorm will take during its track, whether it will bring hail or just rain, or when there will ...
Tafferner, A., Forster, C.
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Short-term Load Forecasting Based On Variational Mode Decomposition And Chaotic Grey Wolf Optimization Improved Random Forest Algorithm

open access: yesJournal of Applied Science and Engineering, 2022
To enrich short-term load forecasting methods and improve forecasting accuracy, a short-term load forecasting method based on variational mode decomposition and chaotic grey wolf optimization (CGWO) improved random forest (RF) is proposed.
Fan Wang   +3 more
doaj   +1 more source

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