Results 101 to 110 of about 215,326 (298)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Wavelet-based short-term load forecasting using optimized anfis [PDF]

open access: yes, 2016
This paper focuses on forecasting electric load consumption using optimized Adaptive Neuro-Fuzzy inference System (ANFIS). It employs the use of Particle Swarm Optimization (PSO) to optimize ANFIS, with aim of improving its speed and accuracy.
Abubakar, I.   +3 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Enhanced Neuro-Fuzzy Architecture for Electrical Load Forecasting [PDF]

open access: yes, 2010
Previous researches about electrical load time series data forecasting showed that the result was not satisfying. This paper elaborates the enhanced neuro-fuzzy architecture for the same application.
Ferdinando, Hany   +2 more
core   +2 more sources

Intelligent short-term load forecasting in Turkey

open access: yesInternational Journal of Electrical Power & Energy Systems, 2006
Abstract A method is proposed to forecast Turkey’s total electric load one day in advance by neural networks. A hybrid learning scheme that combines off-line learning with real-time forecasting is developed to use the available data for adapting the weights and to further adjust these connections according to changing conditions.
Ayca Kumluca Topalli   +2 more
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Multi-horizon short-term load forecasting using hybrid of LSTM and modified split convolution. [PDF]

open access: yesPeerJ Comput Sci, 2023
Ullah I   +5 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

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