Results 61 to 70 of about 411,065 (301)

Scheduling Jobs in Flowshops with the Introduction of Additional Machines in the Future [PDF]

open access: yes, 2008
This is the author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier and can be found at: http://www.journals.elsevier.com/expert-systems-with-applications/.The problem of scheduling jobs to ...
A. Apostolico   +15 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Fresh Manner Cuckoo Search Algorithm to Hydrothermal Scheduling in Short Term

open access: yesEdison Journal for Electrical and Electronics Engineering
The main goal of the short-term hydrothermal scheduling (HS) challenge is to drastically  reduce the large fuel cost of producing power by scheduling the hydrothermal energy producers  while taking power balance restrictions, the reservoir's storage ...
K. S. Khalaf   +2 more
doaj   +1 more source

Nonlinear optimization method for short-term hydro scheduling considering head-dependency [PDF]

open access: yes, 2010
This paper is on the problem of short-term hydro scheduling, particularly concerning head-dependent reservoirs under competitive environment. We propose a new nonlinear optimization method to consider hydroelectric power generation as a function of water
Catalão, João Paulo da Silva   +3 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Statistical Performances Evaluation of APSO and Improved APSO for Short Term Hydrothermal Scheduling Problem

open access: yesApplied Sciences, 2019
The Accelerated Particle Swarm Optimization (APSO) algorithm is an efficient and the easiest to implement variant of the famous Particle Swarm Optimization (PSO) algorithm.
Muhammad Salman Fakhar   +5 more
doaj   +1 more source

Effectiveness of kanban approaches in systems engineering within rapid response environments [PDF]

open access: yes, 1928
Effective application of systems engineering in rapid response environments has been difficult, particularly those where large, complex brownfield systems or systems of systems exist and are constantly being updated with both short and long term software
Turner, Richard   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Forecasting for day-ahead offshore maintenance scheduling under uncertainty [PDF]

open access: yes, 2016
Offshore wind farm maintenance operations are complex and dangerous, and as such are subject to strict safety constraints. In addition, crew and vessels must be scheduled in advance for both planned and reactive maintenance operations.
Browell, J., Dinwoodie, I., McMillan, D.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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