Results 81 to 90 of about 60,189 (305)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Novel Multiple Time-grid Continuous-time Mathematical Formulation for Short-term Scheduling of Multipurpose Batch Plants. [PDF]

Ind Eng Chem Res, 2022
Li D, Rakovitis N, Zheng T, Pan Y, Li J, Kopanos G.   +5 more
europepmc   +1 more source

SHORT TERM HYDRO THERMAL SCHEDULING PROBLEM: A REVIEW

, 2020
Operation of a system having both hydro and thermal plants is far more complex and is of much more importance in a modern interconnected power system. The objective of the STHS problem is to optimize the electricity production, considering a short-term ...
Sood, Dr.Yog Raj, SURYAKANT, Mr., BISHT, VIMAL SINGH, KUSHWAHA, NIKHIL   +3 more
core   +1 more source

A hybrid method for large-scale short-term scheduling of make-and-pack production processes [PDF]

, 2014
Due to the ongoing trend towards increased product variety, fast-moving consumer goods such as food and beverages, pharmaceuticals, and chemicals are typically manufactured through so-called make-and-pack processes.
Baumann, Philipp, Trautmann, Norbert
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Short-Term Resource Scheduling with Ramp Constraints [Power Generation Scheduling]

, 1997
This paper describes a Lagrangian relaxation-based method to solve the short-term resource scheduling (STRS) problem with ramp constraints. Instead of discretizing the generation levels, the ramp rate constraints are relaxed with the system demand ...
Svoboda, A. J., Li, Chao-An, Tseng, Chung-Li, Johnson, R. B.   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Dynamic task scheduling method for relay satellite networks based on hierarchical reinforcement learning

Tongxin xuebao, 2023
In recent years, with the increasing number of various emergency tasks, how to control the impact on common tasks while ensuring system revenue has become a huge challenge for the dynamic scheduling of relay satellite networks.Aiming at this problem ...
Runzi LIU, Tianci MA, Weihua WU, Chenhong YAO, Qinghai YANG   +4 more
doaj   +2 more sources

Fifty years of scheduling: a survey of milestones [PDF]

, 2009
Scheduling has become a major field within operational research with several hundred publications appearing each year. This paper explores the historical development of the subject since the mid 1950s when the landmark publications started to appear.
Strusevich, Vitaly A., Strusevich, V.A., Potts, Christopher N., Potts, C.N., C N Potts, V A Strusevich   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source