Results 101 to 110 of about 60,189 (305)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Optimal scheduling for microgrids considering long-term and short-term energy storage

International audiencehe seasonal variability of renewable energy output is a critical consideration for microgrids with a high penetration of renewable energy sources.
Chen, Weirong, Liu, Shukui, Gao, Fei, Li, Qi, Ai, Yuxuan, Wang, Tianhong, Qiu, Yibin, Bai, Hao, Benbouzid, Mohamed   +8 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

A short-term scheduling for a hydropower plant chain

International Journal of Electrical Power & Energy Systems, 1998
An optimal control of a hydropower plant chain is introduced. The aim is to meet a predefined power demand and in the same time provide sufficient control capabilities. At first a state-space model of the river chain is presented. Then an optimal feedback control method is developed by introducing Hamiltonian for the system.
J.M. Pursimo, H.K. Antila, M.K. Vilkko, P.A. Lautala   +3 more
openaire   +1 more source

Robust Mouldable Scheduling Using Application Benchmarking For Elastic Enviornments

, 2012
In this paper we present a framework for developing an intelligent job management and scheduling system that utilizes application specific benchmarks to mould jobs onto available resources.
Kureshi, Ibad, Holmes, Violeta, Cooke, David J.   +2 more
core  

Interference-aware convergecast scheduling in wireless sensor/actuator networks for active airflow control applications

, 2014
Emerging wireless sensor/actuator network (WSAN) technology has the potential to enable semi-autonomous airflow control to improve the aerodynamic performance of aircraft.
Dai, Xuewu, Bür, Kaan, Kaan Bür, Omiyi, Peter, Xuewu Dai, Yang Yang, Peter E. Omiyi, Yang, Yang   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Real-time energy resources scheduling considering short-term and very short-term wind forecast

, 2012
This paper proposes an energy resources management methodology based on three distinct time horizons: day-ahead scheduling, hour-ahead scheduling, and real-time scheduling.
Silva, Marco, Vale, Zita, Sousa, Tiago, Morais, H.   +3 more
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Um modelo para a programação da operação de sistemas hidrotérmicos baseado em relaxação lagrangeana [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2009A Programação da Operação do Sistema Elétrico pode ser formulada por um problema de otimização cujo ...
Rodrigues, Rafael Nilson
core