Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Teaching Undergraduate Macroeconomics with the Taylor-Romer Model [PDF]
This paper sets out a version of the Taylor-Romer model of short-run macroeconomic equilibrium which can be used for teaching undergraduate economics principles courses. The aim is to generate a model with the proven advantages of the IS-LM framework but
Paul Turner
core
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Short, early field research courses as a model to increase equity in ecology
EcosphereEcology lags among STEM disciplines in terms of recruiting and retaining undergraduate students from marginalized groups. A keystone element of many ecologists' training is an emphasis on field experiences at the undergraduate level, such as field ...
Katharine J. Ruskin +4 more
doaj +1 more source
Determinants of tuberculosis treatment outcome under directly observed treatment short courses in Adama City, Ethiopia. [PDF]
PLoS One, 2020 Tesema T, Seyoum D, Ejeta E, Tsegaye R.
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
, 2012 ‘Open Learning: Bridge to Success’, a Next Generation Learning Challenges (NGLC) project, is a partnership between The Open University (OU) (UK), Anne Arundel Community College (AACC), the University of Maryland University College (UMUC), and the ...
Arundel, Anne +7 more
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
QT prolongation, torsades de pointes, and sudden death with short courses of chloroquine or hydroxychloroquine as used in COVID-19: A systematic review. [PDF]
Heart Rhythm, 2020 Jankelson L +4 more
europepmc +1 more source
Terry White: A Two-Front Negotiation Exercise [PDF]
, 1986 In the 1980s, teaching the theory and art of negotiation has become more important than ever in the curricula of law schools. As the cost of full-scale litigation has risen, the pressure on litigants to settle short of trial has increased, and the ...
Schrag, Philip G.
core +2 more sources