Results 221 to 230 of about 197,713 (247)

An Edible H2O2 Biosensor for Gastrointestinal Metabolites and Peroxidase Enzyme Quantification

Advanced Healthcare Materials, EarlyView.
We present an edible biosensor for gastric fluid analysis that integrates a caffeic acid–horseradish peroxidase redox system into an edible electrolyte‐gated transistor. The device enables rapid, low‐volume detection of H2O2 and, with minimal modification, metabolites and enzyme activity in simulated gastrointestinal conditions.
Valerio Francesco Annese, Elena Feltri, Pietro Rossi, Valerio Galli, Cristiano Bortolotti, João Paulo Vita Damasceno, Ivan K. Ilic, Dario Natali, Alessandro Luzio, Adrica Kyndiah, Mario Caironi   +10 more
wiley   +1 more source

Cadences of the collective: conspecific stimulation patterns interact with endogenous rhythms to cue socially mediated response shifts. [PDF]

J Exp Biol
Larter LC, Cushing CW, Ryan MJ.
europepmc   +1 more source

Forces behind N- and C-capping of peptidic helices. [PDF]

Chem Commun (Camb)
Mi T, Mattes L, Pewklang T, Hauser K, Burgess K.   +4 more
europepmc   +1 more source

Circular RNA therapeutics: a new class of long-acting RNA medicines for oncology, immunology, and rare diseases. [PDF]

Front Immunol
Ugwu OP, Okon MB, Ogenyi FC, Ugwu JN, Ugwu CN.   +4 more
europepmc   +1 more source

Sequence-based structural/motif and stereochemical analysis of enterococcal surface protein in endodontic. [PDF]

J Conserv Dent Endod
Boreak N, Halawi O, Albulushi KA, Ghazwani WYJ, Zarban RM, Algamdi ASR, Hamzi SA, Ali AH, Bajawi H.   +8 more
europepmc   +1 more source

Peptide structure and silver ion affinity: influence on the formation of α-helices upon metal binding.

Chem Commun (Camb)
Bianchi A, Fromm KM.
europepmc   +1 more source

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Mimicry of Short Linear Motifs by Bacterial Pathogens: A Drugging Opportunity

Trends in Biochemical Sciences, 2020
Bacterial pathogens have developed complex strategies to successfully survive and proliferate within their hosts. Throughout the infection cycle, direct interaction with host cells occurs. Many bacteria have been found to secrete proteins, such as effectors and toxins, directly into the host cell with the potential to interfere with cell regulatory ...
Hugo, Sámano-Sánchez, Toby J, Gibson
openaire   +4 more sources

Exploring Short Linear Motifs Using the ELM Database and Tools

Current Protocols in Bioinformatics, 2017
AbstractThe Eukaryotic Linear Motif (ELM) resource is dedicated to the characterization and prediction of short linear motifs (SLiMs). SLiMs are compact, degenerate peptide segments found in many proteins and essential to almost all cellular processes. However, despite their abundance, SLiMs remain largely uncharacterized.
Gouw, M., Sámano-Sánchez, H., Van Roey, K., Diella, F., Gibson, T., Dinkel, H.   +5 more
openaire   +5 more sources

Attributes of short linear motifs

Mol. BioSyst., 2012
Traditionally, protein-protein interactions were thought to be mediated by large, structured domains. However, it has become clear that the interactome comprises a wide range of binding interfaces with varying degrees of flexibility, ranging from rigid globular domains to disordered regions that natively lack structure.
Davey NE, Van Roey K, Weatheritt RJ, Toedt G, Uyar B, Altenberg B, Budd A, Diella F, Dinkel H, Gibson TJ   +9 more
openaire   +3 more sources

How to Annotate and Submit a Short Linear Motif to the Eukaryotic Linear Motif Resource

2020
Over the past few years, it has become apparent that approximately 35% of the human proteome consists of intrinsically disordered regions. Many of these disordered regions are rich in short linear motifs (SLiMs) which mediate protein-protein interactions. Although these motifs are short and often partially conserved, they are involved in many important
Gouw, Marc, Alvarado-Valverde, Jesús, Čalyševa, Jelena, Diella, Francesca, Kumar, Manjeet, Michael, Sushama, Van Roey, Kim, Dinkel, Holger, Gibson, Toby J.   +8 more
openaire   +3 more sources