Results 41 to 50 of about 2,092,187 (288)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Language in social media is extremely dynamic: new words emerge, trend and disappear, while the meaning of existing words can fluctuate over time. Such dynamics are especially notable during a period of crisis. This work addresses several important tasks
Arendt, Dustin +3 more
core +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
An Intelligent Track Segment Association Method Based on Characteristic-Aware Attention LSTM Network
Accurate track segment association plays an important role in modern sensor data processing systems to ensure the temporal and spatial consistency of target information.
Jiadi Qi, Xiaoke Lu, Jinping Sun
doaj +1 more source
Objective: to evaluate the functional state of cardio, neuro-endocrine and central nervous systems of highly skilled sportsmen of endurance sports under specific load.
T. Bruk +4 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Using the principal model in the preparation of athletes qualified in short-track [PDF]
The materials on the level of development problems of modeling training process in short-track. Analysis of materials preparation and construction of the training process and a change of the training loads. Constructed basic model training process. Shown
Kugaevskij Sergej Aleksandrovich
doaj
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Content-based access to digital video: the Físchlár system and the TREC video track [PDF]
This short paper presents an overview of the Físchlár system - an operational digital library of several hundred hours of video content at Dublin City University which is used by over 1,000 users daily, for a variety of applications.
Smeaton, Alan F.
core +2 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source

