Results 51 to 60 of about 355,693 (298)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Evaluating Short-Wave Effects in Railway Track Using the Rail Surface Signal

open access: yesApplied Sciences, 2022
Condition assessment and maintenance planning of railway infrastructure is a prerequisite for safe and reliable train operation. As the loads are constantly increasing, condition assessment of the track must also be further developed.
Markus Loidolt, Stefan Marschnig
doaj   +1 more source

Advanced Track-to-Orbit correlation techniques for Very Short Arcs

open access: yes, 2023
LAUREA MAGISTRALEIl mantenimento di un catalogo costantemente aggiornato degli stati dinamici per ogni Resident Space Object attorno alla Terra è di cruciale importanza in uno Space Environment in continua espansione.
Pagno, Federico
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Fall-related admissions after fast-track total hip and knee arthroplasty - cause of concern or consequence of success?

open access: yes, 2013
Christoffer C Jørgensen,1,2 Henrik Kehlet1,2 On behalf of the Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group 1Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark;
Kehlet H   +7 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Modellierung einer Leistungsstruktur am Beispiel der Sportart Short Track [PDF]

open access: yes, 2013
Um aufzuklären welche konditionellen Faktoren beim Short Track leistungsbestimmend sind, wurden im Rahmen dieser Arbeit empirische Daten 26 deutscher Short-Track-Athleten statistisch ausgewertet.
Felser, Sabine (gnd: 1038204305)
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Data-Driven Bias Correction and Defect Diagnosis Model for In-Service Vehicle Acceleration Measurements

open access: yesSensors, 2020
Track quality instruments use low-cost accelerometers placed on or attached to the floors of operating trains, and these instruments collect substantial amounts of data over short inspection periods.
Lei Bai, Rengkui Liu, Qing Li
doaj   +1 more source

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