Results 71 to 80 of about 513,470 (287)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Liquidity shortages: theoretical underpinnings. [PDF]
Liquidity shortages arise when financial institutions and industrial companies scramble for, and cannot find the cash they require to meet their most urgent needs or undertake their most valuable projects.
Tirole, J.
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The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Two Kinds of Dental Shortages Fuel One Major Access Problem [PDF]
, 2011 Calls for expanding the dental workforce to address the shortage of dentists in certain geographical areas and of dentists treating Medicaid patients required in meeting the needs of low-income children who will be eligible for dental insurance by ...
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The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Liquidity Shortages and Monetary Policy [PDF]
The paper models the interaction between risk taking in the financial sector and central bank policy for the case of pure illiquidity risk. It is shown that, when bad states are highly unlikely, public provision of liquidity may improve the allocation ...
Gerhard Illing, Jin Cao
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Challenged From the Start: Stories of Student Perseverance and Determination in California's Community Colleges [PDF]
, 2012 Shares ten students' experiences overcoming obstacles to college success and completion, including severe shortages in course offerings, support services, and financial aid and bureaucratic difficulties.
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Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
On the Macroeconomics of Asset Shortages [PDF]
The world has a shortage of financial assets. Asset supply is having a hard time keeping up with the global demand for store of value and collateral by households, corporations, governments, insurance companies, and financial intermediaries more broadly.
Ricardo J. Caballero
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Putting Women's Health Care Disparities on the Map: Examining Racial and Ethnic Disparities at the State Level [PDF]
, 2009 Assesses the racial/ethnic disparities in women's health status, access to and utilization of health care, and social factors such as poverty and gender wage gap by state.
Alina Salganicoff +5 more
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