Results 101 to 110 of about 374,623 (353)

Reduced telomere length is associated with fibrotic joint disease suggesting that impaired telomere repair contributes to joint fibrosis [PDF]

open access: yes, 2018
OBJECTIVE: Joint fibrosis affects many synovial joints (including hip, knee and shoulder) causing stiffness and pain. The mechanism of joint fibrosis remains unknown, although genetic factors may contribute.
Borthwick, LA   +7 more
core  

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang   +15 more
wiley   +1 more source

Protease‐Activated Plasmonic Nanosensors for Predictive Ultrasound‐Guided Photoacoustic Imaging of Tumor Responses to Adoptive T Cell Therapy

open access: yesAdvanced Science, EarlyView.
Protease‐activated plasmonic nanosensors are demonstrated to noninvasively monitor antitumor T cell activity in tumors with anatomical information upon adoptive T cell transfer via ultrasound‐guided photoacoustic imaging. These nanosensors are actuated by granzyme B, a protease secreted by activated cytotoxic T cells during tumor cell killing, which ...
Myeongsoo Kim   +10 more
wiley   +1 more source

A Computational Approach for Human-like Motion Generation in Upper Limb Exoskeletons Supporting Scapulohumeral Rhythms

open access: yes, 2017
This paper proposes a computational approach for generation of reference path for upper-limb exoskeletons considering the scapulohumeral rhythms of the shoulder.
Langari, Reza   +3 more
core   +1 more source

Sharing the Burden of Collective Security in the European Union. Research Note [PDF]

open access: yes, 2009
This article compares European Union (EU) burden-sharing in security governance distinguishing between assurance, prevention, protection, and compellence policies.
Arce M.   +12 more
core   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

open access: yesAdvanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin   +10 more
wiley   +1 more source

Effect of Floating Needle Perfusion Therapy combined with Joint Mobilization on Shoulder Pain of Hemiplegia after Stroke

open access: yes康复学报, 2021
Objective:To observe the effect of floating needle perfusion therapy combined with joint mobilization on shoulder pain of hemiplegia after stroke.
Xin WANG, Hu LI, Xiuyan LU
doaj  

新設大学ソフトボール選手における外傷・障害の特徴 ─ 過去の外傷・障害統計報告との比較から ─ [PDF]

open access: yes, 2009
The purpose of this study to investigate injury by a male and female collegiate softball players. With a male player, much injury locus was shoulder(30%), elbow joint( 13.3%) finger(10%), lumbar part(10%), knee(10%), back (10%), toes(6.7%), joint of hand(
宮崎 重雄   +4 more
core   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

Компьютеризированная система Multi-Joint System MJS 403 Plus в превентивной реабилитации повреждений и заболеваний плечевого сустава. [PDF]

open access: yes, 2016
У статті розглянуто особливості застосування системи Multi-Joint System MJS 403 Plus для забезпечення технологій превентивної реабілітації пошкоджень і захворювань плечового суглоба.
Demydenko, Maryna   +5 more
core  

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