Results 121 to 130 of about 5,586 (254)

Enhancing Specific Stiffness of Nano‐Architected Materials Through Generative AI and Active Learning

Advanced Science, EarlyView.
A structure‐centric generative framework searches voxelated design space directly, coupling a variational autoencoder with multi‐objective optimization and active learning to progressively expand the validated design domain. The discovered nano‐architectures, realized as pyrolytic carbon by two‐photon lithography, deliver 18–23% higher stiffness and 26–
Jinwook Yeo, Peter Serles, Donggeun Park, Julia R. Greer, Seunghwa Ryu   +4 more
wiley   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Transforming Gas Separations with Scalable Carbon Molecular Sieve Membranes Enabled by Chemically Tuned Hollow‐Fiber Precursors

Advanced Science, EarlyView.
We established a broadly tunable network‐polymer platform for polyimide‐based precursor membranes, extendable to various diamines. Ultrahigh selectivity with demonstrated aging resistance, and scalability via hollow fiber CMS engineering collectively establishes broad and lasting impact for the membrane science and engineering communities.
Yuhe Cao, Zhongyun Liu, Zahra Shomali, Jinyoung Kim, Steven Schlosser, Ryan P. Lively, William J. Koros   +6 more
wiley   +1 more source

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

Numerical Simulation of Magnetohydrodynamic Forced Convective Boundary Layer Flow past a Stretching/Shrinking Sheet Prescribed with Variable Heat Flux in the Presence of Heat Source and Constant Suction

Journal of Applied Fluid Mechanics, 2014
A study has been carried out on MHD boundary layer forced convection flow along a shrinking surface with variable heat flux in the presence of heat source. The flow is generated due to linear shrinking of the sheet and is influenced by uniform transverse
S. P. Anjali Devi, J. Wilfred Samuel Raj
doaj  

An Environmental Stable Ionogel‐Based Smart Glove System for Integrated Underwater Communication and Safety Warning

Advanced Science, EarlyView.
This study develops a smart glove by integrating a P(BZMA‐co‐HEA)/IL ionogel with a reconfigurable FPCB for underwater communication and real‐time safety warning. The network‐constrained ionic soft‐space regulation strategy enables mechanical reliability, environmental stability, and sensing adaptability, while the modular FPCB sensor array simplifies ...
Xiaoqin Li, Jianwen Liu, Wenhao Yang, Wenjing Yue, Nam‐Young Kim, Young‐Kee Shin, Song Gao, Eun‐Seong Kim, Yang Li   +8 more
wiley   +1 more source

Synergistic Effects of Separator Architecture and Electrolyte Chemistry on the Electrochemical Stability of Lithium Ion Batteries With Li–Mn Rich Cathodes and µ‐Si Anodes

Advanced Science, EarlyView.
This work reveals that synergistic engineering of separator architecture and electrolyte chemistry determines the long‐term stability of LMR||µ‐Si cell chemistry. The introduction of N, N‐dimethylsulfamoyl fluoride (DMFSA) as a co‐solvent with fluoroethylene carbonate (FEC) promotes robust interphases on both electrodes, effectively mitigates side ...
Marian Cristian Stan, Bärbel Arling, Gerrit Michael Overhoff, Kirstin Darida, Lucas Marquart, Peng Yan, Lara Kersting, Linus Voigt, Laurin Profanter, Hyung‐Tae Kim, Martin Winter, Gunther Brunklaus, Isidora‐Cekic Laskovic   +12 more
wiley   +1 more source

A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery

Advanced Science, EarlyView.
A scalable three‐dimensional braiding strategy integrates silk and glass fibers into customizable artificial ligaments with programmable “J‐shaped” nonlinear mechanics. The silk‐rich architecture supports osseoligamentous integration, while glass fibers provide mechanical reinforcement and biomimetic mineralization cues, enabling strain‐adaptive load ...
Changbo Lu, Daming Liu, Haoxin Zhang, Zhiwei Qiao, Qiuming Gao, Jia Meng, Hongyin Yue, Songkai Li, Shuo Zhang, Tao Yuan, Yun Xue, Hui Jiang, Zhenguo Liu, Yibo Wang, Nirong Bao, Yuli Chen, Xiaojiang Yang   +16 more
wiley   +1 more source

Co‐Design Insights for Mechanically Active Flexible Printed Circuit Boards Through the CurveQuad Origami Robot

Advanced Science, EarlyView.
This paper presents the process of integrating electronics directly into the body sheet of CurveQuad, a small origami robot that can self‐fold, crawl, and steer with a single actuator. The authors design a flexible printed circuit board for the body sheet: the key challenge is to navigate how embedding electronics affects the mechanical properties and ...
Xuelin Wu, Daniel Feshbach, Satviki Vasireddy, Louis Beardell, Bao To, Yuliy Baryshnikov, Cynthia Sung   +6 more
wiley   +1 more source

Phase‐Programmed Microneedles Enable Sequential Hydrogen and Quercetin Release for Scar‐Reduced Regeneration of Burn Wounds

Advanced Science, EarlyView.
A phase‐programmed microneedle patch, comprising a poly (lactic‐co‐glycolic acid) (PLGA) shell and a sulfobutylether‐β‐cyclodextrin (SBECD) core, is designed for sequential hydrogen and quercetin release for scar‐reduced regeneration of burn wounds. ABSTRACT Burn wounds complicated by bacterial infection and fibrotic scarring remain a major clinical ...
Yongnian Zeng, Zhigang Chu, Huiyuan Yang, Wen Zhang, Peng Jiang, Jiapeng Lei, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source