Results 161 to 170 of about 256,371 (360)

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

Hepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein   +21 more
wiley   +1 more source

The Discovery of a Circulatory Shunt in the Gastric Wall which may Explain the Sudden Formation of Peptic Ulcers

, 1949
Wolfe C.D.A.
openalex   +1 more source

Management of hydrocephalus associated with large vestibular schwannomas. [PDF]

Brain Spine
Lemnos L, Troude L, Boucekine M, Gargula S, Balossier A, Régis J, Roche PH.   +6 more
europepmc   +1 more source

Benign External Hydrocephalus in a Subgroup of Autistic Children Prior to Autism Diagnosis

Autism Research, EarlyView.
ABSTRACT Benign external hydrocephalus (BEH) is evident in < 0.6% of births. It is defined by abnormally large cerebrospinal fluid (CSF) volumes in the subarachnoid space (SAS) and otherwise normal neuroimaging findings before 2 years of age. BEH has not been associated with specific developmental disorders and is not treated because it usually ...
Gal Ben‐Arie, Ilan Shelef, Gal Meiri, Idan Menashe, Ilan Dinstein, Ayelet Arazi   +5 more
wiley   +1 more source

A study on the oxidative shunt of glucose metabolism in the brain

, 1959
Osamu Onoda
openalex   +2 more sources

Transverse venous sinus stenting versus cerebrospinal fluid shunting in idiopathic intracranial hypertension: a multi-institutional and multinational database study. [PDF]

J Neurointerv Surg
Intrapiromkul J, Rai AT, Lakhani DA.
europepmc   +1 more source

The fate of thiopurine metabolites after switching to low‐dose thiopurine with allopurinol or thioguanine in IBD patients: A retrospective analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Shunting (hypermethylating) thiopurine metabolism, characterized by excessive 6‐MMPR production and (sub)therapeutic 6‐TGN levels, poses a significant challenge in the treatment of inflammatory bowel disease (IBD). This study evaluates the metabolic outcomes of switching to low‐dose thiopurine with allopurinol (LDTA) or thioguanine (TG) in IBD ...
Ahmed B. Bayoumy, Hedwig M. A. D'Agnolo, Nanne K. H. de Boer, Chris J. J. Mulder, Luc J. J. Derijks   +4 more
wiley   +1 more source

AORTA-ATRIUM SHUNT

, 1957

openalex   +1 more source

Assessment and clinical relevance of pulmonary shunt on ¹⁶⁶Ho-Scout Imaging in hepatocellular carcinoma. [PDF]

EJNMMI Phys
Vranken E, De Crop A, Nuttens V, Vandenbulcke R, Dewaele T, Ryckaert T, Decaestecker J, De Meulder S, De Bondt P.   +8 more
europepmc   +1 more source

Shunting Inhibition Modulates Neuronal Gain during Synaptic Excitation

Neuron, 2003
Simon J. Mitchell, R. Silver
semanticscholar   +1 more source